Assessment of cardiac iron deposition and genotypic classification in pediatric beta-thalassemia major: the role of cardiac MRI

Assessment of cardiac iron deposition and genotypic classification in pediatric beta-thalassemia major: the role of cardiac MRI

Abstract Background Beta thalassemia major (β-TM) is a severe genetic anemia with considerable phenotypic heterogeneity. This study investigated whether genotype correlates with distinct myocardial iron overload patterns, assessed by cardiovascular magnetic resonance (CMR) T2* values. Methods CMR da...

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Bibliographic Details
Main Authors: Siqi Zhang, Wen Zhao, Longwei Sun, Guohua Liang, Xiaodong Wang, Hongwu Zeng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medical Imaging
Subjects:
Β-thalassemia major
Cardiac MRI
Iron deposition
Genotype
Paediatric
Online Access:https://doi.org/10.1186/s12880-025-01567-7
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