Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn.
The present study was aimed to investigate the in vitro free radical scavenging activity of various leaf extracts (aqueous, methanol, acetone chloroform and petroleum ether) of Kedrostis foetidissima. In vitro free radical scavenging activities of the extracts were assessed against DPPH and hydroxyl...
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| Language: | English |
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Tsinghua University Press
2015-03-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453015000130 |
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| author | Kalaisezhiyen Pavithra Sasikumar Vadivukkarasi |
| author_facet | Kalaisezhiyen Pavithra Sasikumar Vadivukkarasi |
| author_sort | Kalaisezhiyen Pavithra |
| collection | DOAJ |
| description | The present study was aimed to investigate the in vitro free radical scavenging activity of various leaf extracts (aqueous, methanol, acetone chloroform and petroleum ether) of Kedrostis foetidissima. In vitro free radical scavenging activities of the extracts were assessed against DPPH and hydroxyl radicals. The metal chelating activity and reducing power ability of the extracts were also determined. The free radical scavenging activity was found to be high in methanolic extract for DPPH and hydroxyl radicals in a concentration dependent manner followed by chloroform, aqueous, acetone and petroleum ether extracts. The metal chelating activity and reducing power ability was also found to be high in methanolic extract. The difference in scavenging potential of the extracts may be due to variation in the percentage of phytoconstituents extracted in various solvents. Thus the result suggests that the methanolic leaf extract of K. foetidissima could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases. |
| format | Article |
| id | doaj-art-c0b6c4aed057463eacd3ecd17de69cdc |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2015-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-c0b6c4aed057463eacd3ecd17de69cdc2025-02-03T06:35:00ZengTsinghua University PressFood Science and Human Wellness2213-45302015-03-0141424610.1016/j.fshw.2015.02.001Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn.Kalaisezhiyen PavithraSasikumar VadivukkarasiThe present study was aimed to investigate the in vitro free radical scavenging activity of various leaf extracts (aqueous, methanol, acetone chloroform and petroleum ether) of Kedrostis foetidissima. In vitro free radical scavenging activities of the extracts were assessed against DPPH and hydroxyl radicals. The metal chelating activity and reducing power ability of the extracts were also determined. The free radical scavenging activity was found to be high in methanolic extract for DPPH and hydroxyl radicals in a concentration dependent manner followed by chloroform, aqueous, acetone and petroleum ether extracts. The metal chelating activity and reducing power ability was also found to be high in methanolic extract. The difference in scavenging potential of the extracts may be due to variation in the percentage of phytoconstituents extracted in various solvents. Thus the result suggests that the methanolic leaf extract of K. foetidissima could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases.http://www.sciencedirect.com/science/article/pii/S2213453015000130Free radicalsKedrostis foetidissimaAntioxidantsPhenolsScavenging activity |
| spellingShingle | Kalaisezhiyen Pavithra Sasikumar Vadivukkarasi Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. Food Science and Human Wellness Free radicals Kedrostis foetidissima Antioxidants Phenols Scavenging activity |
| title | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. |
| title_full | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. |
| title_fullStr | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. |
| title_full_unstemmed | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. |
| title_short | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. |
| title_sort | evaluation of free radical scavenging activity of various extracts of leaves from kedrostis foetidissima jacq cogn |
| topic | Free radicals Kedrostis foetidissima Antioxidants Phenols Scavenging activity |
| url | http://www.sciencedirect.com/science/article/pii/S2213453015000130 |
| work_keys_str_mv | AT kalaisezhiyenpavithra evaluationoffreeradicalscavengingactivityofvariousextractsofleavesfromkedrostisfoetidissimajacqcogn AT sasikumarvadivukkarasi evaluationoffreeradicalscavengingactivityofvariousextractsofleavesfromkedrostisfoetidissimajacqcogn |