E3RC: A step-by-step computational protocol for exploring enhancer RNA expression and regulation using conventional RNA-seq data

E3RC: A step-by-step computational protocol for exploring enhancer RNA expression and regulation using conventional RNA-seq data

Summary: Here, we present a computational framework, E3RC, for exploring enhancer RNA (eRNA) expression and regulation using conventional RNA sequencing (RNA-seq) data. Using a public dataset as an example, we describe step-by-step guidelines for identifying eRNAs and characterizing their expression...

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Bibliographic Details
Main Authors: Hua Yu, Yunjie Liu, Zhouming Zhang, Guanglei Xie, Jingyu Liu, Yijia Liu, Siyue He, Zhiwei Peng, Lu Lu, Fei Li, Xi Wang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:STAR Protocols
Subjects:
Bioinformatics
RNAseq
Sequence analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725003958
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