Claustrum modulation drives altered prefrontal cortex dynamics and connectivity

Abstract This study delves into the claustrum’s role in modulating spontaneous and sensory-evoked network activity across cortical regions. Using mesoscale calcium imaging and Gi and Gq DREADDs in anesthetized mice, we show that decreasing claustral activity enhances prefrontal cortical activity, wh...

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Bibliographic Details
Main Authors: Ryan Zahacy, Yonglie Ma, Ian R. Winship, Jesse Jackson, Allen W. Chan
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07256-5
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