Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl

Urticaria is common in children. Urticarial vasculitis (UV) is a potentially more serious, rare variant. The youngest reported case was 12 months of age. A systemically well, 19-month-old girl presented with her mother who was concerned about the development of a rash. On presentation, the child had...

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Main Author: Peter Williams
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2016/1691290
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author Peter Williams
author_facet Peter Williams
author_sort Peter Williams
collection DOAJ
description Urticaria is common in children. Urticarial vasculitis (UV) is a potentially more serious, rare variant. The youngest reported case was 12 months of age. A systemically well, 19-month-old girl presented with her mother who was concerned about the development of a rash. On presentation, the child had normal vital signs, was alert, and was well and playing with toys. There was a widespread urticarial rash (raised, pruritic, and erythematous) that was most apparent on the trunk with minimal rash on the legs. Overlying this urticarial rash in a similar distribution was a blotchy, palpable purpuric rash and associated hyperpigmentation. Investigations revealed a normal level of haemoglobin, white cells, platelets, and electrolytes. Renal function, international normalised ratio, and activated partial thromboplastin time were all normal. There was no blood or protein in the urine. The erythrocyte sedimentation rate was mildly elevated at 19 mm/hour. Complement results (including C1q) obtained later were normal. This case is striking not only because of the rarity of UV in children but also due to the unique diagnostic and prognostic challenges that it raises.
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spelling doaj-art-c085a1a9aeee4b2dabde3caf2a62af742025-02-03T05:51:56ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/16912901691290Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old GirlPeter Williams0Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Grattan Street, Parkville, VIC, AustraliaUrticaria is common in children. Urticarial vasculitis (UV) is a potentially more serious, rare variant. The youngest reported case was 12 months of age. A systemically well, 19-month-old girl presented with her mother who was concerned about the development of a rash. On presentation, the child had normal vital signs, was alert, and was well and playing with toys. There was a widespread urticarial rash (raised, pruritic, and erythematous) that was most apparent on the trunk with minimal rash on the legs. Overlying this urticarial rash in a similar distribution was a blotchy, palpable purpuric rash and associated hyperpigmentation. Investigations revealed a normal level of haemoglobin, white cells, platelets, and electrolytes. Renal function, international normalised ratio, and activated partial thromboplastin time were all normal. There was no blood or protein in the urine. The erythrocyte sedimentation rate was mildly elevated at 19 mm/hour. Complement results (including C1q) obtained later were normal. This case is striking not only because of the rarity of UV in children but also due to the unique diagnostic and prognostic challenges that it raises.http://dx.doi.org/10.1155/2016/1691290
spellingShingle Peter Williams
Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
Case Reports in Pediatrics
title Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
title_full Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
title_fullStr Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
title_full_unstemmed Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
title_short Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl
title_sort normocomplementaemic urticarial vasculitis in a 19 month old girl
url http://dx.doi.org/10.1155/2016/1691290
work_keys_str_mv AT peterwilliams normocomplementaemicurticarialvasculitisina19montholdgirl