C/EBPβ–VCAM1 axis in Kupffer cells promotes hepatic inflammation in MASLD

C/EBPβ–VCAM1 axis in Kupffer cells promotes hepatic inflammation in MASLD

Background & Aims: Kupffer cells (KCs) can promote hepatic inflammation in metabolic dysfunction-associated steatotic liver disease (MASLD), but the underlying molecular mechanisms are not fully understood. C/EBPβ in macrophages can mediate metabolic and immune dysregulations. Therefore, we...

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Bibliographic Details
Main Authors: Shuang-Zhe Lin, Yang Xie, Yu-Qing Cheng, Rui Xue, Yin-Shi Su, Mingxi Liu, Yuan-Wen Chen, Jian-Gao Fan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:JHEP Reports
Subjects:
MASLD
MASH
Kupffer cell
VCAM1
C/EBPβ
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555925000953
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