Multi-omics mechanical analysis of gut microbiota, carboxylic acids, and cardiac gene expression interaction triggering diabetic cardiomyopathy

Multi-omics mechanical analysis of gut microbiota, carboxylic acids, and cardiac gene expression interaction triggering diabetic cardiomyopathy

ABSTRACT It is well known that gut microbial imbalance is a potential factor for the occurrence and development of diabetes mellitus (DM) and its complications. Moreover, the heart and gut microbiota can regulate each other through the gut–metabolite–heart axis. In this study, metagenomics, metabolo...

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Bibliographic Details
Main Authors: Meixin Shi, Bingbing Zhao, Wenjie Cai, Hui Yuan, Xiao Liang, Zhitao Li, Xinyu Liu, Ye Jin, Xi Liu, Can Wei
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mSystems
Subjects:
diabetic cardiomyopathy
gut microbiota
PPAR signaling pathway
carboxylic acids
Online Access:https://journals.asm.org/doi/10.1128/msystems.01450-24
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