Inflammation and Macular Oedema after Pars Plana Vitrectomy
Cystoid macular oedema (CMO) is a major cause of reduced vision following intraocular surgery. Although the aetiology of CMO is not completely clarified, intraocular inflammation is known to play a major role in its development. The macula may develop cytotoxic oedema when the primary lesion and flu...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2013/971758 |
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| author | Vito Romano Martina Angi Fabrizio Scotti Renata del Grosso Davide Romano Francesco Semeraro Paolo Vinciguerra Ciro Costagliola Mario R. Romano |
| author_facet | Vito Romano Martina Angi Fabrizio Scotti Renata del Grosso Davide Romano Francesco Semeraro Paolo Vinciguerra Ciro Costagliola Mario R. Romano |
| author_sort | Vito Romano |
| collection | DOAJ |
| description | Cystoid macular oedema (CMO) is a major cause of reduced vision following intraocular surgery. Although the aetiology of CMO is not completely clarified, intraocular inflammation is known to play a major role in its development. The macula may develop cytotoxic oedema when the primary lesion and fluid accumulation occur in the parenchymatous cells (intracellular oedema) or vasogenic oedema when the primary defect occurs in the blood-retinal barrier and leads to extracellular fluid accumulation (extracellular oedema). We report on the mechanisms of CMO formation after pars plana vitrectomy and associated surgical procedures and discuss possible therapeutic approaches. |
| format | Article |
| id | doaj-art-c07a121179104987a3b17d175453b384 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-c07a121179104987a3b17d175453b3842025-02-03T06:07:57ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/971758971758Inflammation and Macular Oedema after Pars Plana VitrectomyVito Romano0Martina Angi1Fabrizio Scotti2Renata del Grosso3Davide Romano4Francesco Semeraro5Paolo Vinciguerra6Ciro Costagliola7Mario R. Romano8Second University of Naples, Via Pansini 5, 80100 Napoli, ItalyDepartment of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UKDepartment of Ophthalmology, Istituto Clinico Humanitas, Rozzano, Milan, ItalyOphthalmology Unit, San Sebastiano Hospital, Caserta, ItalyOphthalmology Unit, San Sebastiano Hospital, Caserta, ItalyEye Clinic, Department of Neurological Sciences and Vision, University of Brescia, Brescia, ItalyDepartment of Ophthalmology, Istituto Clinico Humanitas, Rozzano, Milan, ItalyEye Clinic, Department of Health Sciences, University of Molise, Campobasso, ItalyDepartment of Ophthalmology, Istituto Clinico Humanitas, Rozzano, Milan, ItalyCystoid macular oedema (CMO) is a major cause of reduced vision following intraocular surgery. Although the aetiology of CMO is not completely clarified, intraocular inflammation is known to play a major role in its development. The macula may develop cytotoxic oedema when the primary lesion and fluid accumulation occur in the parenchymatous cells (intracellular oedema) or vasogenic oedema when the primary defect occurs in the blood-retinal barrier and leads to extracellular fluid accumulation (extracellular oedema). We report on the mechanisms of CMO formation after pars plana vitrectomy and associated surgical procedures and discuss possible therapeutic approaches.http://dx.doi.org/10.1155/2013/971758 |
| spellingShingle | Vito Romano Martina Angi Fabrizio Scotti Renata del Grosso Davide Romano Francesco Semeraro Paolo Vinciguerra Ciro Costagliola Mario R. Romano Inflammation and Macular Oedema after Pars Plana Vitrectomy Mediators of Inflammation |
| title | Inflammation and Macular Oedema after Pars Plana Vitrectomy |
| title_full | Inflammation and Macular Oedema after Pars Plana Vitrectomy |
| title_fullStr | Inflammation and Macular Oedema after Pars Plana Vitrectomy |
| title_full_unstemmed | Inflammation and Macular Oedema after Pars Plana Vitrectomy |
| title_short | Inflammation and Macular Oedema after Pars Plana Vitrectomy |
| title_sort | inflammation and macular oedema after pars plana vitrectomy |
| url | http://dx.doi.org/10.1155/2013/971758 |
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