Flow chemistry-enabled asymmetric synthesis of cyproterone acetate in a chemo-biocatalytic approach

Abstract Flow chemistry has many advantages over batch synthesis of organic small-molecules in terms of environmental compatibility, safety and synthetic efficiency when scale-up is considered. Herein, we report the 10-step chemo-biocatalytic continuous flow asymmetric synthesis of cyproterone aceta...

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Bibliographic Details
Main Authors: Yajiao Zhang, Minjie Liu, Xianjing Zheng, Liang Gao, Li Wan, Dang Cheng, Fener Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56371-2
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