FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION
Here we describe the 5-year-follow-up of a female suffering from both tuberculosis (TB) and human immunodeficiency virus (HIV) infection. The management of the patient was particularly complicated due to systemic tuberculosis, multiple organ dysfunction syndrome, weakened immunity, and tre...
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| Format: | Article |
| Language: | Russian |
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Kemerovo State Medical University
2018-03-01
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| Series: | Фундаментальная и клиническая медицина |
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| Online Access: | https://fcm.kemsmu.ru/jour/article/view/85 |
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| author | TATYANA V. Pyanzova NATALIA V. Luzinа OLGA N. Kononchuk |
| author_facet | TATYANA V. Pyanzova NATALIA V. Luzinа OLGA N. Kononchuk |
| author_sort | TATYANA V. Pyanzova |
| collection | DOAJ |
| description | Here we describe the 5-year-follow-up of a female suffering from both tuberculosis (TB) and human immunodeficiency virus (HIV) infection. The management of the patient was particularly complicated due to systemic tuberculosis, multiple organ dysfunction syndrome, weakened immunity, and treatment intolerance. The patient received highly active antiretroviral therapy (HAART) for the whole period of follow-up, with two courses of anti-TB treatment over 39 months. Despite the development of an immune reconstitution inflammatory syndrome, aggressive treatment prevented the death and stabilized clinical course, with the further successful TB eradication. Five years after the diagnosis, we did not observe any signs of TB relapse. Patient’s general conditions was satisfactory. Immune status has been also improved, presumably due to HAART. We conclude that even patients with HIV infection combined with systemic TB may have a favorable prognosis. |
| format | Article |
| id | doaj-art-c0686efdf41d42e6bc5007d6ed12eefa |
| institution | Kabale University |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2018-03-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-c0686efdf41d42e6bc5007d6ed12eefa2025-08-20T03:57:40ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412018-03-013110211084FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTIONTATYANA V. Pyanzova0NATALIA V. Luzinа1OLGA N. Kononchuk2Kemerovo State Medical UniversityKemerovo Regional Clinical Anti-Tuberculosis DispensaryKemerovo Regional Center for AIDS Prevention and ControlHere we describe the 5-year-follow-up of a female suffering from both tuberculosis (TB) and human immunodeficiency virus (HIV) infection. The management of the patient was particularly complicated due to systemic tuberculosis, multiple organ dysfunction syndrome, weakened immunity, and treatment intolerance. The patient received highly active antiretroviral therapy (HAART) for the whole period of follow-up, with two courses of anti-TB treatment over 39 months. Despite the development of an immune reconstitution inflammatory syndrome, aggressive treatment prevented the death and stabilized clinical course, with the further successful TB eradication. Five years after the diagnosis, we did not observe any signs of TB relapse. Patient’s general conditions was satisfactory. Immune status has been also improved, presumably due to HAART. We conclude that even patients with HIV infection combined with systemic TB may have a favorable prognosis.https://fcm.kemsmu.ru/jour/article/view/85вич-инфекциятуберкулез множественных локализацийтуберкулез периферических лимфатических узловвысокоактивная антиретровирусная терапиясиндром восстановления иммунной системыhiv infectionsystemic tuberculosisperipheral lymph node tuberculosishighly active antiretroviral therapyimmune reconstitution inflammatory syndrome |
| spellingShingle | TATYANA V. Pyanzova NATALIA V. Luzinа OLGA N. Kononchuk FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION Фундаментальная и клиническая медицина вич-инфекция туберкулез множественных локализаций туберкулез периферических лимфатических узлов высокоактивная антиретровирусная терапия синдром восстановления иммунной системы hiv infection systemic tuberculosis peripheral lymph node tuberculosis highly active antiretroviral therapy immune reconstitution inflammatory syndrome |
| title | FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION |
| title_full | FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION |
| title_fullStr | FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION |
| title_full_unstemmed | FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION |
| title_short | FIVE-YEAR OBSERVATION OF THE PATIENT WITH SYSTEMIC TUBERCULOSIS AND HIV-INFECTION |
| title_sort | five year observation of the patient with systemic tuberculosis and hiv infection |
| topic | вич-инфекция туберкулез множественных локализаций туберкулез периферических лимфатических узлов высокоактивная антиретровирусная терапия синдром восстановления иммунной системы hiv infection systemic tuberculosis peripheral lymph node tuberculosis highly active antiretroviral therapy immune reconstitution inflammatory syndrome |
| url | https://fcm.kemsmu.ru/jour/article/view/85 |
| work_keys_str_mv | AT tatyanavpyanzova fiveyearobservationofthepatientwithsystemictuberculosisandhivinfection AT nataliavluzina fiveyearobservationofthepatientwithsystemictuberculosisandhivinfection AT olgankononchuk fiveyearobservationofthepatientwithsystemictuberculosisandhivinfection |