Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma
Background/Aim. Few studies have reported the prognostic value of pretreatment hemoglobin levels in patients with lung adenocarcinoma (LA). In the present study, we retrospectively reviewed 306 LA patients for their prognosis associated with the pretreatment hemoglobin levels. Methods. Person-years...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2018/6328127 |
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| author | Yue-Hua Zhang Yuquan Lu Hong Lu Meng-Wei Zhang Yue-Min Zhou Xiang-Lei Li |
| author_facet | Yue-Hua Zhang Yuquan Lu Hong Lu Meng-Wei Zhang Yue-Min Zhou Xiang-Lei Li |
| author_sort | Yue-Hua Zhang |
| collection | DOAJ |
| description | Background/Aim. Few studies have reported the prognostic value of pretreatment hemoglobin levels in patients with lung adenocarcinoma (LA). In the present study, we retrospectively reviewed 306 LA patients for their prognosis associated with the pretreatment hemoglobin levels. Methods. Person-years and case fatality rate (CFR) were calculated from May 2010 to June 2017. Hazard ratio (HR) and 95% confidence intervals (CIs) were estimated using the Cox proportional hazards regression analysis. Survival curves were generated using the Kaplan–Meier analysis. Results. Patients with low pretreatment hemoglobin (LPHb) levels had a higher CFR than did patients with normal pretreatment hemoglobin (NPHb) levels (HR = 1.48, 95% CI = 1.06–2.08, and P=0.023). Overall survival of NPHb patients was significantly higher than that of LPHb patients (P<0.05). Conclusion. Low pretreatment hemoglobin level was demonstrated to be an independent biomarker for poor prognosis in patients with LA. |
| format | Article |
| id | doaj-art-c062a93a504d40af8a0f384f9ae1eb51 |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-c062a93a504d40af8a0f384f9ae1eb512025-02-03T05:52:48ZengWileyCanadian Respiratory Journal1198-22411916-72452018-01-01201810.1155/2018/63281276328127Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung AdenocarcinomaYue-Hua Zhang0Yuquan Lu1Hong Lu2Meng-Wei Zhang3Yue-Min Zhou4Xiang-Lei Li5Department of Oncology, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaInternational Joint Research Laboratory for Cell Medical Engineering of Henan, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaDepartment of Oncology, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaDepartment of Oncology, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaInternational Joint Research Laboratory for Cell Medical Engineering of Henan, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaDepartment of Oncology, Huaihe Hospital of Henan University, Kaifeng 475001, ChinaBackground/Aim. Few studies have reported the prognostic value of pretreatment hemoglobin levels in patients with lung adenocarcinoma (LA). In the present study, we retrospectively reviewed 306 LA patients for their prognosis associated with the pretreatment hemoglobin levels. Methods. Person-years and case fatality rate (CFR) were calculated from May 2010 to June 2017. Hazard ratio (HR) and 95% confidence intervals (CIs) were estimated using the Cox proportional hazards regression analysis. Survival curves were generated using the Kaplan–Meier analysis. Results. Patients with low pretreatment hemoglobin (LPHb) levels had a higher CFR than did patients with normal pretreatment hemoglobin (NPHb) levels (HR = 1.48, 95% CI = 1.06–2.08, and P=0.023). Overall survival of NPHb patients was significantly higher than that of LPHb patients (P<0.05). Conclusion. Low pretreatment hemoglobin level was demonstrated to be an independent biomarker for poor prognosis in patients with LA.http://dx.doi.org/10.1155/2018/6328127 |
| spellingShingle | Yue-Hua Zhang Yuquan Lu Hong Lu Meng-Wei Zhang Yue-Min Zhou Xiang-Lei Li Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma Canadian Respiratory Journal |
| title | Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma |
| title_full | Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma |
| title_fullStr | Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma |
| title_full_unstemmed | Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma |
| title_short | Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma |
| title_sort | pretreatment hemoglobin level is an independent prognostic factor in patients with lung adenocarcinoma |
| url | http://dx.doi.org/10.1155/2018/6328127 |
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