SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury

SOX9 mediates the phenotypic transformation of vascular smooth muscle cells in restenosis after carotid artery injury

In-stent restenosis (ISR) remains a significant public health challenge globally, as millions of stents are implanted annually. Elucidating the mechanisms underlying ISR is essential for developing effective preventive and therapeutic strategies. In this study, we identified SOX9, a transcription fa...

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Bibliographic Details
Main Authors: Chuan Jiang, Jiasen Ye, Jie Huang, Yang Gao, Hong Chen, Fuqiang Guo, Lei Guo, Xiaofan Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SOX9
signal transducer and activator of transcription 3
vascular smooth muscle cells
transformation
proliferation
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1592594/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1592594/full

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