Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report

Hyalinizing clear cell carcinoma (HCCC), also known as clear cell carcinoma is a rare tumor constituting ≤1% of minor salivary gland tumors. We present here the case of a 48-year-old woman with complaints of pain in the left lower jaw with a surgical history of post-marginal mandibulectomy (lesion b...

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Main Authors: Mohsina Hussain, Arif Shaikh, Rajendra Dhongde, Sucheta Gandhe, Yogesh Pawar, Sirshendu Roy, Raj Nagarkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-12-01
Series:Journal of Head & Neck Physicians and Surgeons
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Online Access:https://journals.lww.com/10.4103/jhnps.jhnps_97_22
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author Mohsina Hussain
Arif Shaikh
Rajendra Dhongde
Sucheta Gandhe
Yogesh Pawar
Sirshendu Roy
Raj Nagarkar
author_facet Mohsina Hussain
Arif Shaikh
Rajendra Dhongde
Sucheta Gandhe
Yogesh Pawar
Sirshendu Roy
Raj Nagarkar
author_sort Mohsina Hussain
collection DOAJ
description Hyalinizing clear cell carcinoma (HCCC), also known as clear cell carcinoma is a rare tumor constituting ≤1% of minor salivary gland tumors. We present here the case of a 48-year-old woman with complaints of pain in the left lower jaw with a surgical history of post-marginal mandibulectomy (lesion being benign). However, the postoperative histopathological reports confirmed clear cell carcinoma of the mandible. Due to delay in presenting, a whole-body positron emission tomography scan was performed and reports have shown no evidence of disease elsewhere in the body. Immunohistochemistry was performed and reports suggested HCCC of salivary gland origin. The patient underwent segmental resection of the mandible along with bilateral modified radical neck dissection and reconstruction of the defect with a free fibula flap. The postoperative period was uneventful. The clinical characteristics, differential diagnosis, surgery, histological, immunohistochemical, and treatment for HCCC were reviewed and discussed.
format Article
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institution Kabale University
issn 2347-8128
language English
publishDate 2023-12-01
publisher Wolters Kluwer Medknow Publications
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series Journal of Head & Neck Physicians and Surgeons
spelling doaj-art-c044fb998c96442580011da39de6aea12025-01-23T05:50:09ZengWolters Kluwer Medknow PublicationsJournal of Head & Neck Physicians and Surgeons2347-81282023-12-0111212612910.4103/jhnps.jhnps_97_22Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case ReportMohsina HussainArif ShaikhRajendra DhongdeSucheta GandheYogesh PawarSirshendu RoyRaj NagarkarHyalinizing clear cell carcinoma (HCCC), also known as clear cell carcinoma is a rare tumor constituting ≤1% of minor salivary gland tumors. We present here the case of a 48-year-old woman with complaints of pain in the left lower jaw with a surgical history of post-marginal mandibulectomy (lesion being benign). However, the postoperative histopathological reports confirmed clear cell carcinoma of the mandible. Due to delay in presenting, a whole-body positron emission tomography scan was performed and reports have shown no evidence of disease elsewhere in the body. Immunohistochemistry was performed and reports suggested HCCC of salivary gland origin. The patient underwent segmental resection of the mandible along with bilateral modified radical neck dissection and reconstruction of the defect with a free fibula flap. The postoperative period was uneventful. The clinical characteristics, differential diagnosis, surgery, histological, immunohistochemical, and treatment for HCCC were reviewed and discussed.https://journals.lww.com/10.4103/jhnps.jhnps_97_22case reportfree fibula flaphyalinizing clear cell carcinomamandibulectomymodified radical neck dissection
spellingShingle Mohsina Hussain
Arif Shaikh
Rajendra Dhongde
Sucheta Gandhe
Yogesh Pawar
Sirshendu Roy
Raj Nagarkar
Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
Journal of Head & Neck Physicians and Surgeons
case report
free fibula flap
hyalinizing clear cell carcinoma
mandibulectomy
modified radical neck dissection
title Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
title_full Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
title_fullStr Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
title_full_unstemmed Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
title_short Hyalinizing Clear Cell Carcinoma of the Mandible – A Rare Case Report
title_sort hyalinizing clear cell carcinoma of the mandible a rare case report
topic case report
free fibula flap
hyalinizing clear cell carcinoma
mandibulectomy
modified radical neck dissection
url https://journals.lww.com/10.4103/jhnps.jhnps_97_22
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