Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy
Peripheral pulmonary lesions (PPLs) present a significant diagnostic challenge due to their location beyond the reach of traditional bronchoscopy. With lung cancer being the leading cause of cancer-related mortality worldwide, accurate and early diagnosis of PPLs is crucial. Virtual bronchoscopic n...
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PAGEPress Publications
2025-01-01
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| Series: | Monaldi Archives for Chest Disease |
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| Online Access: | https://www.monaldi-archives.org/macd/article/view/3223 |
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| author | Parul Mrigpuri Sidharth Raj Yadav Divyendu Sharma Sonam Spalgais Vidushi Rathi Nitin Goel Balakrishnan Menon Raj Kumar |
| author_facet | Parul Mrigpuri Sidharth Raj Yadav Divyendu Sharma Sonam Spalgais Vidushi Rathi Nitin Goel Balakrishnan Menon Raj Kumar |
| author_sort | Parul Mrigpuri |
| collection | DOAJ |
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Peripheral pulmonary lesions (PPLs) present a significant diagnostic challenge due to their location beyond the reach of traditional bronchoscopy. With lung cancer being the leading cause of cancer-related mortality worldwide, accurate and early diagnosis of PPLs is crucial. Virtual bronchoscopic navigation (VBN) combined with radial endobronchial ultrasound (R-EBUS) has emerged as a promising technique to enhance the diagnostic yield for these lesions. This retrospective observational study evaluated the diagnostic yield of VBN-guided R-EBUS in patients with PPLs identified on computed tomography. The study included nine patients who underwent VBN-guided R-EBUS biopsy sampling. Patient demographics, lesion characteristics, and procedural outcomes were analyzed using descriptive and inferential statistics. The mean age of the patients was 57.33 years, with a mean lesion size of 3.24 cm. The diagnostic yield of VBN-guided R-EBUS was 77.7% (95% confidence interval: 68.5-85.8%). Non-small cell carcinoma was the most frequent histopathological diagnosis (55.5%). Complications included bleeding in two patients (22.2%) and bronchospasm in one patient (11.1%), all managed conservatively. VBN-guided R-EBUS provides high diagnostic accuracy and a low risk of complications in patients with PPLs.
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| format | Article |
| id | doaj-art-c039482668ac4b8696aa3caf6d4d054b |
| institution | Kabale University |
| issn | 1122-0643 2532-5264 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Monaldi Archives for Chest Disease |
| spelling | doaj-art-c039482668ac4b8696aa3caf6d4d054b2025-01-30T01:39:46ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642025-01-0110.4081/monaldi.2025.3223Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracyParul Mrigpuri0https://orcid.org/0000-0001-7723-4866Sidharth Raj Yadav1Divyendu Sharma2Sonam Spalgais3https://orcid.org/0000-0001-7116-2486Vidushi Rathi4https://orcid.org/0000-0003-0432-2624Nitin Goel5https://orcid.org/0000-0001-5155-8985Balakrishnan Menon6Raj Kumar7Department of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New DelhiDepartment of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi Peripheral pulmonary lesions (PPLs) present a significant diagnostic challenge due to their location beyond the reach of traditional bronchoscopy. With lung cancer being the leading cause of cancer-related mortality worldwide, accurate and early diagnosis of PPLs is crucial. Virtual bronchoscopic navigation (VBN) combined with radial endobronchial ultrasound (R-EBUS) has emerged as a promising technique to enhance the diagnostic yield for these lesions. This retrospective observational study evaluated the diagnostic yield of VBN-guided R-EBUS in patients with PPLs identified on computed tomography. The study included nine patients who underwent VBN-guided R-EBUS biopsy sampling. Patient demographics, lesion characteristics, and procedural outcomes were analyzed using descriptive and inferential statistics. The mean age of the patients was 57.33 years, with a mean lesion size of 3.24 cm. The diagnostic yield of VBN-guided R-EBUS was 77.7% (95% confidence interval: 68.5-85.8%). Non-small cell carcinoma was the most frequent histopathological diagnosis (55.5%). Complications included bleeding in two patients (22.2%) and bronchospasm in one patient (11.1%), all managed conservatively. VBN-guided R-EBUS provides high diagnostic accuracy and a low risk of complications in patients with PPLs. https://www.monaldi-archives.org/macd/article/view/3223Peripheral pulmonary lesionradial endobronchial ultrasoundvirtual bronchoscopic navigation |
| spellingShingle | Parul Mrigpuri Sidharth Raj Yadav Divyendu Sharma Sonam Spalgais Vidushi Rathi Nitin Goel Balakrishnan Menon Raj Kumar Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy Monaldi Archives for Chest Disease Peripheral pulmonary lesion radial endobronchial ultrasound virtual bronchoscopic navigation |
| title | Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy |
| title_full | Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy |
| title_fullStr | Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy |
| title_full_unstemmed | Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy |
| title_short | Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy |
| title_sort | virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions harmonizing modalities to optimize accuracy |
| topic | Peripheral pulmonary lesion radial endobronchial ultrasound virtual bronchoscopic navigation |
| url | https://www.monaldi-archives.org/macd/article/view/3223 |
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