Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts

Abstract Electrochemical co‐reduction of carbon dioxide and nitrates (CO2NO3RR) holds promise for sustainable urea production. However, the sluggish kinetics of the sixteen‐electron transfer and unclear mechanistic understanding strongly impede its development. Here, combined experimental and comput...

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Main Authors: Qinglan Zhao, Yushen Liu, Yuan Zhang, Shangqian Zhu, Hongming Xu, Mohammad Farhadpour, Fei Xiao, Minghui Xing, Dapeng Cao, Xueping Qin, Tejs Vegge, Minhua Shao
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
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Online Access:https://doi.org/10.1002/advs.202501882
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author Qinglan Zhao
Yushen Liu
Yuan Zhang
Shangqian Zhu
Hongming Xu
Mohammad Farhadpour
Fei Xiao
Minghui Xing
Dapeng Cao
Xueping Qin
Tejs Vegge
Minhua Shao
author_facet Qinglan Zhao
Yushen Liu
Yuan Zhang
Shangqian Zhu
Hongming Xu
Mohammad Farhadpour
Fei Xiao
Minghui Xing
Dapeng Cao
Xueping Qin
Tejs Vegge
Minhua Shao
author_sort Qinglan Zhao
collection DOAJ
description Abstract Electrochemical co‐reduction of carbon dioxide and nitrates (CO2NO3RR) holds promise for sustainable urea production. However, the sluggish kinetics of the sixteen‐electron transfer and unclear mechanistic understanding strongly impede its development. Here, combined experimental and computational approaches are employed to screen a series of metal phthalocyanine as model catalysts (MPcs, M = Zn, Co, Ni, Cu, and Fe) to uncover the activity‐selectivity trends in electrochemical CO2NO3RR. The theoretical simulations reveal that the thermodynamics of urea synthesis is significantly influenced by key intermediates, where the enhanced adsorption of *HOOCNO, coupled with reduced adsorptions of *N and *COOH, and moderate adsorption of *H2O, can significantly promote the urea production. ΔG*HOOCNO−ΔG*N−ΔG*COOH+ΔG*H2O as a potential descriptor is proposed for predicting the efficiency of CO2NO3RR toward urea formation. The findings provide systematic guidance for the future design of high‐efficiency catalysts for urea electrosynthesis, addressing a crucial need for sustainable nitrogen fixation.
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institution Kabale University
issn 2198-3844
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publishDate 2025-07-01
publisher Wiley
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series Advanced Science
spelling doaj-art-c026a0fd2deb4bbd8a2dedddb9c2cc1b2025-08-20T03:50:58ZengWileyAdvanced Science2198-38442025-07-011227n/an/a10.1002/advs.202501882Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site CatalystsQinglan Zhao0Yushen Liu1Yuan Zhang2Shangqian Zhu3Hongming Xu4Mohammad Farhadpour5Fei Xiao6Minghui Xing7Dapeng Cao8Xueping Qin9Tejs Vegge10Minhua Shao11Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaSchool of Chemistry and Chemical Engineering Southeast University Jiangning District Nanjing Jiangsu 211189 P. R. ChinaDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaState Key Laboratory of Organic‐Inorganic Composites Beijing University of Chemical Technology Beijing 100029 P. R. ChinaState Key Laboratory of Organic‐Inorganic Composites Beijing University of Chemical Technology Beijing 100029 P. R. ChinaDepartment of Energy Conversion and Storage Technical University of Denmark Lyngby 2800 Kgs. DenmarkDepartment of Energy Conversion and Storage Technical University of Denmark Lyngby 2800 Kgs. DenmarkDepartment of Chemical and Biological Engineering The Hong Kong University of Science and Technology Clear Water Bay, Kowloon Hong Kong P. R. ChinaAbstract Electrochemical co‐reduction of carbon dioxide and nitrates (CO2NO3RR) holds promise for sustainable urea production. However, the sluggish kinetics of the sixteen‐electron transfer and unclear mechanistic understanding strongly impede its development. Here, combined experimental and computational approaches are employed to screen a series of metal phthalocyanine as model catalysts (MPcs, M = Zn, Co, Ni, Cu, and Fe) to uncover the activity‐selectivity trends in electrochemical CO2NO3RR. The theoretical simulations reveal that the thermodynamics of urea synthesis is significantly influenced by key intermediates, where the enhanced adsorption of *HOOCNO, coupled with reduced adsorptions of *N and *COOH, and moderate adsorption of *H2O, can significantly promote the urea production. ΔG*HOOCNO−ΔG*N−ΔG*COOH+ΔG*H2O as a potential descriptor is proposed for predicting the efficiency of CO2NO3RR toward urea formation. The findings provide systematic guidance for the future design of high‐efficiency catalysts for urea electrosynthesis, addressing a crucial need for sustainable nitrogen fixation.https://doi.org/10.1002/advs.202501882activity‐selectivity trendC‐N couplingco‐reduction reactionelectrocatalysissingle‐site catalyst
spellingShingle Qinglan Zhao
Yushen Liu
Yuan Zhang
Shangqian Zhu
Hongming Xu
Mohammad Farhadpour
Fei Xiao
Minghui Xing
Dapeng Cao
Xueping Qin
Tejs Vegge
Minhua Shao
Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
Advanced Science
activity‐selectivity trend
C‐N coupling
co‐reduction reaction
electrocatalysis
single‐site catalyst
title Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
title_full Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
title_fullStr Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
title_full_unstemmed Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
title_short Activity‐Selectivity Trends in Electrochemical Urea Synthesis: Co‐Reduction of CO2 and Nitrates Over Single‐Site Catalysts
title_sort activity selectivity trends in electrochemical urea synthesis co reduction of co2 and nitrates over single site catalysts
topic activity‐selectivity trend
C‐N coupling
co‐reduction reaction
electrocatalysis
single‐site catalyst
url https://doi.org/10.1002/advs.202501882
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