Bidirectional modulation of glycolysis using a multifunctional nanocomposite hydrogel promotes bone fracture healing in type 2 diabetes mellitus
Fracture healing in patients with type 2 diabetes mellitus (T2D) is markedly impaired, characterized by a prolonged inflammation phase and defective osteoblast differentiation at the fracture site. In this study, we identified aberrant cellular glycolysis at T2D fracture sites, with bone marrow mese...
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| Main Authors: | Shengming Zhang, Weixian Hu, Yanzhi Zhao, Yuheng Liao, Kangkang Zha, Wenqian Zhang, Chenyan Yu, Jiewen Liao, Hui Li, Wu Zhou, Faqi Cao, Bobin Mi, Guohui Liu |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-08-01
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| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X25001306 |
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