HIV Modulates Osteoblast Differentiation via Upregulation of RANKL and Vitronectin

HIV Modulates Osteoblast Differentiation via Upregulation of RANKL and Vitronectin

Bone loss is a prevalent characteristic among people with HIV (PWH). We focused on mesenchymal stem cells (MSCs) and osteoblasts, examining their susceptibility to different HIV strains (R5- and X4-tropic) and the subsequent effects on bone tissue homeostasis. Our findings suggest that MSCs and oste...

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Bibliographic Details
Main Authors: Rosa Nicole Freiberger, Cynthia Alicia Marcela López, María Belén Palma, Cintia Cevallos, Franco Agustin Sviercz, Patricio Jarmoluk, Marcela Nilda García, Jorge Quarleri, M. Victoria Delpino
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pathogens
Subjects:
osteoblasts
HIV
bone
vitronectin
Online Access:https://www.mdpi.com/2076-0817/13/9/800
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