Association of combined pulmonary fibrosis and emphysema in rheumatoid arthritis with high titer of rheumatoid factor and autoimmunity to the lung

Association of combined pulmonary fibrosis and emphysema in rheumatoid arthritis with high titer of rheumatoid factor and autoimmunity to the lung

BackgroundCombined pulmonary fibrosis and emphysema (CPFE) commonly coexists with connective tissue diseases (CTD), such as rheumatoid arthritis (RA). However, the risk factors contributing to the development of CTD-CPFE remain largely unidentified. This study aimed to characterize CPFE using a larg...

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Bibliographic Details
Main Authors: Aiping Ma, Renliang Huang, Jiaxi Guo, Guangdong Wang, Heqing Huang, Xinze Li, Shan Zhong, Yan Huang, Shaowei Lin, Yikai Lin, Qiaomiao Zhou, Susanne Krauss-Etschmann, Frank Petersen, Zhanxiang Wang, Xinhua Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
combined pulmonary fibrosis and emphysema (CPFE)
connective tissue diseases (CTD)
rheumatoid arthritis (RA)
autoimmunity
rheumatoid factor (RF)
human bronchial epithelial cells (HBEC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1514552/full
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