Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancer

Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancer

Therapy-resistant ovarian cancers have a poor prognosis and novel effective treatment options are urgently needed. In this study, we evaluated the therapeutic efficacy of the oncolytic vesicular stomatitis virus (VSV) against a panel of patient-derived ovarian cancer cell lines of all epithelial sub...

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Bibliographic Details
Main Authors: Karen Geoffroy, Victor Mullins-Dansereau, Kim Leclerc-Desaulniers, Mélissa Viens, Marie-Claude Bourgeois-Daigneault
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Molecular Therapy: Oncology
Subjects:
ovarian cancer
oncolytic virus
VSV
JAK inhibitors
ruxolitinib
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924000687
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