A High-Fat Diet Induces Oxidative Stress in OPA1<sup>+/−</sup> Mouse Cortices: A Critical Double Challenge

A High-Fat Diet Induces Oxidative Stress in OPA1<sup>+/−</sup> Mouse Cortices: A Critical Double Challenge

A high-fat diet (HFD) has significant effects on health, leading to cardiovascular, metabolic, neurodegenerative, and psychiatric conditions and contributing to obesity and type 2 diabetes. Mitochondria, essential for energy production and oxidative metabolism, are adversely affected by a HFD, causi...

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Bibliographic Details
Main Authors: Camille Champigny, Marlène Botella, Djamaa Atamena, Sébastien Bullich, Corentin Coustham, Bruno Guiard, Pascale Belenguer, Noélie Davezac
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antioxidants
Subjects:
cortices
antioxidant defenses
mitochondria
OPA1
neurodegenerative disease
Online Access:https://www.mdpi.com/2076-3921/14/7/876
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