Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio
Introduction: Endothelial dysfunction, marked by a high ET-1/NO ratio, plays a key role in preeclampsia. Prenatal yoga may improve endothelial function by enhancing blood flow and cardiovascular regulation Objective: This study aimed to evaluate the effect of a structured prenatal yoga program on...
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2025-08-01
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| Series: | Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación |
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| Online Access: | https://revistaretos.org/index.php/retos/article/view/116846 |
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| author | Hamimatus Zainiyah Bambang Purwanto Ernawati Ernawati Raden Argarini Mukhoirotin Mukhoirotin |
| author_facet | Hamimatus Zainiyah Bambang Purwanto Ernawati Ernawati Raden Argarini Mukhoirotin Mukhoirotin |
| author_sort | Hamimatus Zainiyah |
| collection | DOAJ |
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Introduction: Endothelial dysfunction, marked by a high ET-1/NO ratio, plays a key role in preeclampsia. Prenatal yoga may improve endothelial function by enhancing blood flow and cardiovascular regulation
Objective: This study aimed to evaluate the effect of a structured prenatal yoga program on the ET-1/NO ratio in pregnant women at high risk of developing preeclampsia.
Methodology: An experimental study was carried out involving 46 pregnant women with clinical risk factors for preeclampsia, recruited between 9 and 16 weeks of gestation. Participants were randomly allocated to either a yoga intervention group (n = 23) or a control group (n = 23). All participants received standard care consisting of low-dose aspirin (80 mg/day) and calcium supplementation (1 g/day). The intervention group additionally attended 20 supervised prenatal yoga sessions over a four-week period. Serum concentrations of ET-1 and NO were measured before and after the intervention. The primary outcome was the change in the ET-1/NO ratio.
Results: The yoga intervention group demonstrated a significant reduction in the ET-1/NO ratio, from 1.13 ± 0.42 to 0.94 ± 0.38 ng/mL (p = 0.010), while the control group showed a significant increase from 0.85 ± 0.29 to 1.01 ± 0.38 ng/mL (p = 0.049).
Discussion: Findings suggest that prenatal yoga may enhance endothelial function in high-risk pregnancies by balancing vasoconstrictive and vasodilatory factors through stress reduction and vascular regulation.
Conclusions: Prenatal yoga can be considered a promising complementary approach to improve endothelial function and potentially prevent preeclampsia in high-risk pregnant women
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| format | Article |
| id | doaj-art-bfbef96c73c54b78ad787c7520a4176b |
| institution | Kabale University |
| issn | 1579-1726 1988-2041 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | FEADEF |
| record_format | Article |
| series | Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación |
| spelling | doaj-art-bfbef96c73c54b78ad787c7520a4176b2025-08-20T03:38:55ZengFEADEFRetos: Nuevas Tendencias en Educación Física, Deportes y Recreación1579-17261988-20412025-08-017010.47197/retos.v70.116846Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratioHamimatus Zainiyah0https://orcid.org/0000-0002-1682-363XBambang Purwanto1Ernawati Ernawati2Raden Argarini3Mukhoirotin Mukhoirotin4Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga (Indonesia) ; Department of Midwifery,Universitas Noor Huda MustofaDepartment of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga (Indonesia)Department of Obstetric Gynecology, Faculty of Medicine, Universitas Airlangga (Indonesia)Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga (Indonesia)Department of Nursing, Faculty of Health Science, Universitas Pesantren Tinggi Darul Ulum (Indonesia) Introduction: Endothelial dysfunction, marked by a high ET-1/NO ratio, plays a key role in preeclampsia. Prenatal yoga may improve endothelial function by enhancing blood flow and cardiovascular regulation Objective: This study aimed to evaluate the effect of a structured prenatal yoga program on the ET-1/NO ratio in pregnant women at high risk of developing preeclampsia. Methodology: An experimental study was carried out involving 46 pregnant women with clinical risk factors for preeclampsia, recruited between 9 and 16 weeks of gestation. Participants were randomly allocated to either a yoga intervention group (n = 23) or a control group (n = 23). All participants received standard care consisting of low-dose aspirin (80 mg/day) and calcium supplementation (1 g/day). The intervention group additionally attended 20 supervised prenatal yoga sessions over a four-week period. Serum concentrations of ET-1 and NO were measured before and after the intervention. The primary outcome was the change in the ET-1/NO ratio. Results: The yoga intervention group demonstrated a significant reduction in the ET-1/NO ratio, from 1.13 ± 0.42 to 0.94 ± 0.38 ng/mL (p = 0.010), while the control group showed a significant increase from 0.85 ± 0.29 to 1.01 ± 0.38 ng/mL (p = 0.049). Discussion: Findings suggest that prenatal yoga may enhance endothelial function in high-risk pregnancies by balancing vasoconstrictive and vasodilatory factors through stress reduction and vascular regulation. Conclusions: Prenatal yoga can be considered a promising complementary approach to improve endothelial function and potentially prevent preeclampsia in high-risk pregnant women https://revistaretos.org/index.php/retos/article/view/116846Biomarker modulation blood pressureprenatal exerciserelaxation |
| spellingShingle | Hamimatus Zainiyah Bambang Purwanto Ernawati Ernawati Raden Argarini Mukhoirotin Mukhoirotin Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación Biomarker modulation blood pressure prenatal exercise relaxation |
| title | Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio |
| title_full | Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio |
| title_fullStr | Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio |
| title_full_unstemmed | Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio |
| title_short | Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio |
| title_sort | structured prenatal yoga on endothelial function in high risk preeclampsia of pregnant women focusing on et 1 no ratio |
| topic | Biomarker modulation blood pressure prenatal exercise relaxation |
| url | https://revistaretos.org/index.php/retos/article/view/116846 |
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