Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy

ABSTRACT Rosai‐Dorfman disease is a rare histiocytic disorder that can mimic malignancies. This case highlights the importance of immunohistochemistry in distinguishing RDD from lymphoproliferative neoplasms, ensuring accurate diagnosis and management. Clinicians should consider RDD in unexplained s...

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Main Authors: Allahdad Khan, Anam Malik, Muhammad Hussnain Sadiq, Muhammad Shahzaib Arshad, Fatima Safdar, Mohamed Antar
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.70463
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author Allahdad Khan
Anam Malik
Muhammad Hussnain Sadiq
Muhammad Shahzaib Arshad
Fatima Safdar
Mohamed Antar
author_facet Allahdad Khan
Anam Malik
Muhammad Hussnain Sadiq
Muhammad Shahzaib Arshad
Fatima Safdar
Mohamed Antar
author_sort Allahdad Khan
collection DOAJ
description ABSTRACT Rosai‐Dorfman disease is a rare histiocytic disorder that can mimic malignancies. This case highlights the importance of immunohistochemistry in distinguishing RDD from lymphoproliferative neoplasms, ensuring accurate diagnosis and management. Clinicians should consider RDD in unexplained soft tissue masses to avoid misdiagnosis and unnecessary interventions.
format Article
id doaj-art-bfaada6d8a6e42c4b15a1d2ef352f36f
institution OA Journals
issn 2050-0904
language English
publishDate 2025-04-01
publisher Wiley
record_format Article
series Clinical Case Reports
spelling doaj-art-bfaada6d8a6e42c4b15a1d2ef352f36f2025-08-20T02:18:33ZengWileyClinical Case Reports2050-09042025-04-01134n/an/a10.1002/ccr3.70463Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical LymphadenopathyAllahdad Khan0Anam Malik1Muhammad Hussnain Sadiq2Muhammad Shahzaib Arshad3Fatima Safdar4Mohamed Antar5Department of Medicine Nishtar Medical University Multan PakistanDepartment of Pathology Nishtar Medical University Multan PakistanDepartment of Medicine Nishtar Medical University Multan PakistanDepartment of Surgery The Aga Khan University Karachi PakistanDepartment of Pathology & Laboratory Medicine The Aga Khan University Karachi PakistanFaculty of Medicine Tishreen University Latakia Syrian Arab RepublicABSTRACT Rosai‐Dorfman disease is a rare histiocytic disorder that can mimic malignancies. This case highlights the importance of immunohistochemistry in distinguishing RDD from lymphoproliferative neoplasms, ensuring accurate diagnosis and management. Clinicians should consider RDD in unexplained soft tissue masses to avoid misdiagnosis and unnecessary interventions.https://doi.org/10.1002/ccr3.70463cervical lymphadenopathyemperipolesisimmunohistochemistryRosai‐Dorfman diseasesinus histiocytosis
spellingShingle Allahdad Khan
Anam Malik
Muhammad Hussnain Sadiq
Muhammad Shahzaib Arshad
Fatima Safdar
Mohamed Antar
Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
Clinical Case Reports
cervical lymphadenopathy
emperipolesis
immunohistochemistry
Rosai‐Dorfman disease
sinus histiocytosis
title Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
title_full Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
title_fullStr Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
title_full_unstemmed Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
title_short Rosai‐Dorfman Disease in a 4‐Month‐Old Female Presenting With Cervical Lymphadenopathy
title_sort rosai dorfman disease in a 4 month old female presenting with cervical lymphadenopathy
topic cervical lymphadenopathy
emperipolesis
immunohistochemistry
Rosai‐Dorfman disease
sinus histiocytosis
url https://doi.org/10.1002/ccr3.70463
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