Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure

We report a case of early latent syphilis (reactive serologic tests without clinical evidence of disease within 24 months from the onset of the infection) in pregnancy. Despite an appropriate maternal treatment with benzathine penicillin G, sonographic signs of fetal syphilis were detected. Follow-u...

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Main Authors: Lucia Pasquini, Elena Rita Magro-Malosso, Adalgisa Cordisco, Michele Trotta, Mariarosaria Di Tommaso
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2018/8706738
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author Lucia Pasquini
Elena Rita Magro-Malosso
Adalgisa Cordisco
Michele Trotta
Mariarosaria Di Tommaso
author_facet Lucia Pasquini
Elena Rita Magro-Malosso
Adalgisa Cordisco
Michele Trotta
Mariarosaria Di Tommaso
author_sort Lucia Pasquini
collection DOAJ
description We report a case of early latent syphilis (reactive serologic tests without clinical evidence of disease within 24 months from the onset of the infection) in pregnancy. Despite an appropriate maternal treatment with benzathine penicillin G, sonographic signs of fetal syphilis were detected. Follow-up scans, in addiction to serial serological tests, have allowed the identification of fetal infection and therefore the failure of antibiotic therapy. We highlight the importance of ultrasound in suspecting fetal infection and in evaluation of the fetal response after penicillin treatment.
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institution Kabale University
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language English
publishDate 2018-01-01
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-bf9ef98cb5dd4366ba18a497b3c649522025-02-03T01:23:24ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/87067388706738Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment FailureLucia Pasquini0Elena Rita Magro-Malosso1Adalgisa Cordisco2Michele Trotta3Mariarosaria Di Tommaso4Maternal and Child Department, Careggi University Hospital Florence, Florence, ItalyMaternal and Child Department, Careggi University Hospital Florence, Florence, ItalyMaternal and Child Department, Careggi University Hospital Florence, Florence, ItalyInfectious Disease Unit, Careggi University Hospital Florence, Florence, ItalyMaternal and Child Department, Careggi University Hospital Florence, Florence, ItalyWe report a case of early latent syphilis (reactive serologic tests without clinical evidence of disease within 24 months from the onset of the infection) in pregnancy. Despite an appropriate maternal treatment with benzathine penicillin G, sonographic signs of fetal syphilis were detected. Follow-up scans, in addiction to serial serological tests, have allowed the identification of fetal infection and therefore the failure of antibiotic therapy. We highlight the importance of ultrasound in suspecting fetal infection and in evaluation of the fetal response after penicillin treatment.http://dx.doi.org/10.1155/2018/8706738
spellingShingle Lucia Pasquini
Elena Rita Magro-Malosso
Adalgisa Cordisco
Michele Trotta
Mariarosaria Di Tommaso
Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
Case Reports in Obstetrics and Gynecology
title Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
title_full Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
title_fullStr Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
title_full_unstemmed Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
title_short Latent Syphilis Infection in Pregnancy: An Ultrasound Diagnosed Case of Penicillin Treatment Failure
title_sort latent syphilis infection in pregnancy an ultrasound diagnosed case of penicillin treatment failure
url http://dx.doi.org/10.1155/2018/8706738
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AT adalgisacordisco latentsyphilisinfectioninpregnancyanultrasounddiagnosedcaseofpenicillintreatmentfailure
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