Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature
Introduction. The extramedullary plasmacytomas (EMPs) are rare tumors of plasma cell disorders which are rarely found in the duodenum. We presented a case of solitary EMPs involving the duodenum and pancreas successfully treated by surgical resection after failure of chemotherapy. Case repo...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500142I.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850241652554203136 |
|---|---|
| author | Ignjatović Mile Bezmarević Mihailo Cerović Snežana |
| author_facet | Ignjatović Mile Bezmarević Mihailo Cerović Snežana |
| author_sort | Ignjatović Mile |
| collection | DOAJ |
| description | Introduction. The extramedullary plasmacytomas (EMPs) are rare tumors of
plasma cell disorders which are rarely found in the duodenum. We presented a
case of solitary EMPs involving the duodenum and pancreas successfully
treated by surgical resection after failure of chemotherapy. Case report. A
55-year-old female with previously diagnosed solitary EMP of the duodenum was
admitted to our institution after failure of three cycles of vincristine,
adriablastine, dexamethasone (VAD) chemotherapy regimen with an upper
gastrointestinal obstruction. On admission computed tomography of the abdomen
showed tumor in the region of the second part of duodenum and uncinate
process of the pancreas with a complete duodenal obstruction.
Intraoperatively a tumor formation was in the region of the second duodenal
part, originated from the wall of duodenum with the total diameter of 7 x 5 cm, covering the entire circumference of duodenal wall leaded to a narrowing
of duodenal lumen to the thigh gap with an upper gastrointestinal
obstruction. Infiltration in the head of the pancreas and uncinate process were also found. The Whipple’s procedure was performed but postoperative
course was complicated by rapidly refilling chylous ascites which was
resolved 4 days after the surgery. Conclusion. Each patient with
gastrointestinal EMPs should be considered separately and in timely manner,
thus adequate treatment could provide local disease control. |
| format | Article |
| id | doaj-art-bf26d0c7ed3845d0a61bc2aa1b7a7c0b |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-bf26d0c7ed3845d0a61bc2aa1b7a7c0b2025-08-20T02:00:33ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202016-01-0173440240710.2298/VSP141031142I0042-84501500142ISolitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literatureIgnjatović Mile0Bezmarević Mihailo1Cerović Snežana2Military Medical Academy, Clinic for General Surgery, Belgrade + University of Defense, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for General Surgery, Belgrade + University of Defense, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defense, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic Medicine, BelgradeIntroduction. The extramedullary plasmacytomas (EMPs) are rare tumors of plasma cell disorders which are rarely found in the duodenum. We presented a case of solitary EMPs involving the duodenum and pancreas successfully treated by surgical resection after failure of chemotherapy. Case report. A 55-year-old female with previously diagnosed solitary EMP of the duodenum was admitted to our institution after failure of three cycles of vincristine, adriablastine, dexamethasone (VAD) chemotherapy regimen with an upper gastrointestinal obstruction. On admission computed tomography of the abdomen showed tumor in the region of the second part of duodenum and uncinate process of the pancreas with a complete duodenal obstruction. Intraoperatively a tumor formation was in the region of the second duodenal part, originated from the wall of duodenum with the total diameter of 7 x 5 cm, covering the entire circumference of duodenal wall leaded to a narrowing of duodenal lumen to the thigh gap with an upper gastrointestinal obstruction. Infiltration in the head of the pancreas and uncinate process were also found. The Whipple’s procedure was performed but postoperative course was complicated by rapidly refilling chylous ascites which was resolved 4 days after the surgery. Conclusion. Each patient with gastrointestinal EMPs should be considered separately and in timely manner, thus adequate treatment could provide local disease control.http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500142I.pdfplasmocytomaduodenumpancreasintestinal obstructionsurgical procedures, operativepostoperative periodascitestreatment outcometreatment outcome |
| spellingShingle | Ignjatović Mile Bezmarević Mihailo Cerović Snežana Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature Vojnosanitetski Pregled plasmocytoma duodenum pancreas intestinal obstruction surgical procedures, operative postoperative period ascites treatment outcome treatment outcome |
| title | Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature |
| title_full | Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature |
| title_fullStr | Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature |
| title_full_unstemmed | Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature |
| title_short | Solitary extramedullary plasmacytoma of the duodenum and pancreas: A case report and review of the literature |
| title_sort | solitary extramedullary plasmacytoma of the duodenum and pancreas a case report and review of the literature |
| topic | plasmocytoma duodenum pancreas intestinal obstruction surgical procedures, operative postoperative period ascites treatment outcome treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500142I.pdf |
| work_keys_str_mv | AT ignjatovicmile solitaryextramedullaryplasmacytomaoftheduodenumandpancreasacasereportandreviewoftheliterature AT bezmarevicmihailo solitaryextramedullaryplasmacytomaoftheduodenumandpancreasacasereportandreviewoftheliterature AT cerovicsnezana solitaryextramedullaryplasmacytomaoftheduodenumandpancreasacasereportandreviewoftheliterature |