Perfluorooctanoic acid disrupts thyroid hormone biosynthesis by altering glycosylation of Na+/I− symporter in larval zebrafish

Perfluorooctanoic acid (PFOA) is a well-known thyroid disruptor that has been found to induce hypothyroidism. However, the exact molecular mechanism by which PFOA reduces thyroid hormone levels remains unclear. In this study, we have discovered that PFOA disrupts the glycosylation process of the sod...

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Bibliographic Details
Main Authors: Zhenzhen Cai, Guangdi Zhou, Xiaogang Yu, Yatao Du, Qiuhong Man, Weiye Charles Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325005858
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