Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway

Triptolide alleviates psoriasis through inhibiting the Wnt5a/β-Catenin signaling pathway

BackgroundPsoriasis, an immune-mediated chronic inflammatory skin disease, is characterized by keratinocyte proliferation and inflammatory cell infiltration. T ripterygium wilfordii is a potential treatment option for psoriasis, and triptolide (TP) is one of its active components. TP may possess the...

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Bibliographic Details
Main Authors: Eryang Chen, Lei Wang, Qu Wang, Yan Cai, Yaning Dou, Hongyan Qu, Junyi Zhu, Haiyang Zhao, Suqing Zheng, Chengguang Zhao, Bin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
psoriasis
triptolide
interleukin-17A
Wnt5a/β-catenin
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1534118/full
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