Acute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypes.

Defects in cilium and centrosome function result in a spectrum of clinically-related disorders, known as ciliopathies. However, the complex molecular composition of these structures confounds functional dissection of what any individual gene product is doing under normal and disease conditions. As p...

Full description

Saved in:
Bibliographic Details
Main Authors: Emma A Hall, Margaret Keighren, Matthew J Ford, Tracey Davey, Andrew P Jarman, Lee B Smith, Ian J Jackson, Pleasantine Mill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1003928
Tags: Add Tag
No Tags, Be the first to tag this record!