Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion
We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/830469 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567128787517440 |
|---|---|
| author | M. J. Levy I. Robertson T. A. Howlett |
| author_facet | M. J. Levy I. Robertson T. A. Howlett |
| author_sort | M. J. Levy |
| collection | DOAJ |
| description | We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum prolactin was significantly elevated at 54,700 miU/L (50–400) confirming a macro-prolactinoma. Within a few days of cabergoline therapy the headache resolved. He continues to be headache free several years after starting the dopamine agonist. This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache. |
| format | Article |
| id | doaj-art-bef449ab6718418980045a6e7c188349 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-bef449ab6718418980045a6e7c1883492025-02-03T01:02:19ZengWileyCase Reports in Neurological Medicine2090-66682090-66762012-01-01201210.1155/2012/830469830469Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus InvasionM. J. Levy0I. Robertson1T. A. Howlett2Department of Endocrinology, Leicester Royal Infirmary, Leicester LE1 5WW, UKDepartment of Neurosurgery, Queens Medical Centre, Nottingham NG7 2UH, UKDepartment of Endocrinology, Leicester Royal Infirmary, Leicester LE1 5WW, UKWe present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum prolactin was significantly elevated at 54,700 miU/L (50–400) confirming a macro-prolactinoma. Within a few days of cabergoline therapy the headache resolved. He continues to be headache free several years after starting the dopamine agonist. This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache.http://dx.doi.org/10.1155/2012/830469 |
| spellingShingle | M. J. Levy I. Robertson T. A. Howlett Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion Case Reports in Neurological Medicine |
| title | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
| title_full | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
| title_fullStr | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
| title_full_unstemmed | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
| title_short | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
| title_sort | cluster headache secondary to macroprolactinoma with ipsilateral cavernous sinus invasion |
| url | http://dx.doi.org/10.1155/2012/830469 |
| work_keys_str_mv | AT mjlevy clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion AT irobertson clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion AT tahowlett clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion |