A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia
Aortitis is a broad term describing inflammation of the aorta. The most common causes of aortitis are the large-vessel vasculitides giant cell arteritis and Takayasu arteritis. Other etiologies include aortitis associated with other autoimmune disorders, infectious causes, and paraneoplastic and idi...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2017/3091973 |
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| author | Sylwia Sasinowska Pamela Traisak Michael McCormack Hala Eid |
| author_facet | Sylwia Sasinowska Pamela Traisak Michael McCormack Hala Eid |
| author_sort | Sylwia Sasinowska |
| collection | DOAJ |
| description | Aortitis is a broad term describing inflammation of the aorta. The most common causes of aortitis are the large-vessel vasculitides giant cell arteritis and Takayasu arteritis. Other etiologies include aortitis associated with other autoimmune disorders, infectious causes, and paraneoplastic and idiopathic cases. We describe a rare case of a large-vessel arteritis occurring in association with chronic myelomonocytic leukemia (CMML). A 68-year-old female with recent diagnosis of CMML presented to our office for evaluation of abnormal chest computed tomography (CT) that showed inflammation surrounding the entirety of thoracic and abdominal aorta, consistent with aortitis. In the absence of other evident causes of large-vessel vasculitis, we attributed this finding to a paraneoplastic autoimmune phenomenon and started treatment with systemic glucocorticoids. This rare case emphasizes the need to recognize autoimmune complications in CMML and treat the inflammation along with the primary malignancy promptly. |
| format | Article |
| id | doaj-art-beec314a387743c3a256875fb0f77737 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-beec314a387743c3a256875fb0f777372025-02-03T05:46:17ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/30919733091973A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic LeukemiaSylwia Sasinowska0Pamela Traisak1Michael McCormack2Hala Eid3Division of Rheumatology, Cooper University Hospital, Camden, NJ, USADivision of Rheumatology, Cooper University Hospital, Camden, NJ, USADivision of Hematology-Oncology, MD Anderson Cancer Center, Cooper University Hospital, Camden, NJ, USADivision of Rheumatology, Cooper University Hospital, Camden, NJ, USAAortitis is a broad term describing inflammation of the aorta. The most common causes of aortitis are the large-vessel vasculitides giant cell arteritis and Takayasu arteritis. Other etiologies include aortitis associated with other autoimmune disorders, infectious causes, and paraneoplastic and idiopathic cases. We describe a rare case of a large-vessel arteritis occurring in association with chronic myelomonocytic leukemia (CMML). A 68-year-old female with recent diagnosis of CMML presented to our office for evaluation of abnormal chest computed tomography (CT) that showed inflammation surrounding the entirety of thoracic and abdominal aorta, consistent with aortitis. In the absence of other evident causes of large-vessel vasculitis, we attributed this finding to a paraneoplastic autoimmune phenomenon and started treatment with systemic glucocorticoids. This rare case emphasizes the need to recognize autoimmune complications in CMML and treat the inflammation along with the primary malignancy promptly.http://dx.doi.org/10.1155/2017/3091973 |
| spellingShingle | Sylwia Sasinowska Pamela Traisak Michael McCormack Hala Eid A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia Case Reports in Hematology |
| title | A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia |
| title_full | A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia |
| title_fullStr | A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia |
| title_full_unstemmed | A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia |
| title_short | A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia |
| title_sort | rare case of paraneoplastic aortitis associated with chronic myelomonocytic leukemia |
| url | http://dx.doi.org/10.1155/2017/3091973 |
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