Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia
In 2012, Canadian pharmacies experienced a shortage of trimethoprim-sulfamethoxazole tablets. Drug shortages may result in unintended clinical consequences such as infection with pathogens against which the alternative medication is ineffective. This is highlighted in the present article, which desc...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2013/805797 |
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| _version_ | 1832556356915167232 |
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| author | Terry C Wuerz Eric J Bow Matthew D Seftel |
| author_facet | Terry C Wuerz Eric J Bow Matthew D Seftel |
| author_sort | Terry C Wuerz |
| collection | DOAJ |
| description | In 2012, Canadian pharmacies experienced a shortage of trimethoprim-sulfamethoxazole tablets. Drug shortages may result in unintended clinical consequences such as infection with pathogens against which the alternative medication is ineffective. This is highlighted in the present article, which describes a case of brain abscess due to Nocardia species that developed while receiving dapsone as an alternative for prophylaxis against Pneumocystis jirovecii pneumonia in a highly immune-suppressed patient. Clinicians should be cognizant of these issues when prescribing alternative agents. |
| format | Article |
| id | doaj-art-bee8c8fb44284c76a43de1440310ebd0 |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-bee8c8fb44284c76a43de1440310ebd02025-02-03T05:45:40ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-0124315916110.1155/2013/805797Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii PneumoniaTerry C Wuerz0Eric J Bow1Matthew D Seftel2Department of Internal Medicine, Section of Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Internal Medicine, Section of Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Internal Medicine, Section of Haematology/Oncology, University of Manitoba, Winnipeg, Manitoba, CanadaIn 2012, Canadian pharmacies experienced a shortage of trimethoprim-sulfamethoxazole tablets. Drug shortages may result in unintended clinical consequences such as infection with pathogens against which the alternative medication is ineffective. This is highlighted in the present article, which describes a case of brain abscess due to Nocardia species that developed while receiving dapsone as an alternative for prophylaxis against Pneumocystis jirovecii pneumonia in a highly immune-suppressed patient. Clinicians should be cognizant of these issues when prescribing alternative agents.http://dx.doi.org/10.1155/2013/805797 |
| spellingShingle | Terry C Wuerz Eric J Bow Matthew D Seftel Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia |
| title_full | Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia |
| title_fullStr | Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia |
| title_full_unstemmed | Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia |
| title_short | Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia |
| title_sort | potential consequences of essential drug shortages in canada brain abscess due to nocardia farcinica associated with dapsone prophylaxis for pneumocystis jirovecii pneumonia |
| url | http://dx.doi.org/10.1155/2013/805797 |
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