S-Nitrosoglutathione Is Not a Substrate of OATP1B1, but Stimulates Its Expression and Activity

S-Nitrosoglutathione Is Not a Substrate of OATP1B1, but Stimulates Its Expression and Activity

S-nitrosoglutathione (GSNO) is the S-nitrosated derivative of glutathione (GSH). GSNO is an endogenous class of NO donors and a natural NO depot in biological systems. Organic anion transporting polypeptide 1B1 (OATP1B1) is an influx transporter that is expressed in the liver. OATP1B1 plays an impor...

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Bibliographic Details
Main Authors: Yulia V. Abalenikhina, Aleksey V. Shchulkin, Olga N. Suchkova, Pelageya D. Ananyeva, Pavel Yu. Mylnikov, Elena N. Yakusheva, Igor A. Suchkov, Roman E. Kalinin
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
Subjects:
S-Nitrosoglutathione
OATP1B1
NO-cGMP signaling pathway
LXR<i>a</i>
Nrf2
Online Access:https://www.mdpi.com/2218-273X/15/3/428
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