Relationship between cognitive impairment and hippocampal iron overload: A quantitative susceptibility mapping study of a rat model

Relationship between cognitive impairment and hippocampal iron overload: A quantitative susceptibility mapping study of a rat model

Background: The aim of this study was to establish an iron overload rat model to simulate the elevated iron levels in patients with thalassemia and to investigate the potential association between hippocampal iron deposition and cognition. Methods: Two groups of iron overloaded rats and one group of...

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Bibliographic Details
Main Authors: Xi Deng, Meiru Bu, Jiali Liang, Yihao Sun, Liyan Li, Heishu Zheng, Zisan Zeng, Muliang Jiang, Bihong T. Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:NeuroImage
Subjects:
Quantitative susceptibility mapping
Thalassemia
Iron overload
Cognitive impairment
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811925000060
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