Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease

Early studies from tertiary referral centers in the United States and Europe showed that patients with long-standing and extensive inflammatory bowel disease (IBD) have an increased risk of colon cancer. It was subsequently appreciated that the degree of risk depended on the population being stu...

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Main Author: Hugh J Freeman
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/472192
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author Hugh J Freeman
author_facet Hugh J Freeman
author_sort Hugh J Freeman
collection DOAJ
description Early studies from tertiary referral centers in the United States and Europe showed that patients with long-standing and extensive inflammatory bowel disease (IBD) have an increased risk of colon cancer. It was subsequently appreciated that the degree of risk depended on the population being studied and on both genetic and environmental factors (eg diet, drugs and prior surgical treatment). Indeed, over the past decade or so, the effects of chronically administered medications, including 5-aminosalicylates (5-ASA), have been explored.
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spelling doaj-art-bee0469e16cb4823ab62cde3fd2f08dd2025-02-03T01:25:38ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-0118640740810.1155/2004/472192Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel DiseaseHugh J FreemanEarly studies from tertiary referral centers in the United States and Europe showed that patients with long-standing and extensive inflammatory bowel disease (IBD) have an increased risk of colon cancer. It was subsequently appreciated that the degree of risk depended on the population being studied and on both genetic and environmental factors (eg diet, drugs and prior surgical treatment). Indeed, over the past decade or so, the effects of chronically administered medications, including 5-aminosalicylates (5-ASA), have been explored.http://dx.doi.org/10.1155/2004/472192
spellingShingle Hugh J Freeman
Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology
title Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
title_full Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
title_fullStr Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
title_full_unstemmed Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
title_short Antineoplastic Effects of 5-Aminosalicylates and Potential Cancer Preventive Role in Inflammatory Bowel Disease
title_sort antineoplastic effects of 5 aminosalicylates and potential cancer preventive role in inflammatory bowel disease
url http://dx.doi.org/10.1155/2004/472192
work_keys_str_mv AT hughjfreeman antineoplasticeffectsof5aminosalicylatesandpotentialcancerpreventiveroleininflammatoryboweldisease