Interstitial Nephritis in a Patient with Inflammatory Bowel Disease

Tubulointerstitial nephritis in patients with inflammatory bowel disease has been linked to the use of 5-ASA derivatives. Various aspects of this theory have been challenged with a potential role for the underlying autoimmune disorder. Steroids are the mainstay of treatment and mycophenolate mofetil...

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Main Authors: Payaswini Vasanth, Michelle Parmley, Jose Torrealba, Tamim Hamdi
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2016/4260365
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author Payaswini Vasanth
Michelle Parmley
Jose Torrealba
Tamim Hamdi
author_facet Payaswini Vasanth
Michelle Parmley
Jose Torrealba
Tamim Hamdi
author_sort Payaswini Vasanth
collection DOAJ
description Tubulointerstitial nephritis in patients with inflammatory bowel disease has been linked to the use of 5-ASA derivatives. Various aspects of this theory have been challenged with a potential role for the underlying autoimmune disorder. Steroids are the mainstay of treatment and mycophenolate mofetil might be an effective alternative. We report a patient who responded well to mycophenolate despite continuing mesalamine, the suspected offending agent.
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institution Kabale University
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publishDate 2016-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-becfd60c6f824288af78408e9d938b152025-02-03T05:54:30ZengWileyCase Reports in Nephrology2090-66412090-665X2016-01-01201610.1155/2016/42603654260365Interstitial Nephritis in a Patient with Inflammatory Bowel DiseasePayaswini Vasanth0Michelle Parmley1Jose Torrealba2Tamim Hamdi3Department of Internal Medicine, Division of Nephrology, UT Southwestern Medical Center, Dallas, TX, USADepartment of Pathology, UT Southwestern Medical Center, Dallas, TX, USADepartment of Pathology, UT Southwestern Medical Center, Dallas, TX, USADepartment of Internal Medicine, Division of Nephrology, UT Southwestern Medical Center, Dallas, TX, USATubulointerstitial nephritis in patients with inflammatory bowel disease has been linked to the use of 5-ASA derivatives. Various aspects of this theory have been challenged with a potential role for the underlying autoimmune disorder. Steroids are the mainstay of treatment and mycophenolate mofetil might be an effective alternative. We report a patient who responded well to mycophenolate despite continuing mesalamine, the suspected offending agent.http://dx.doi.org/10.1155/2016/4260365
spellingShingle Payaswini Vasanth
Michelle Parmley
Jose Torrealba
Tamim Hamdi
Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
Case Reports in Nephrology
title Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
title_full Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
title_fullStr Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
title_full_unstemmed Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
title_short Interstitial Nephritis in a Patient with Inflammatory Bowel Disease
title_sort interstitial nephritis in a patient with inflammatory bowel disease
url http://dx.doi.org/10.1155/2016/4260365
work_keys_str_mv AT payaswinivasanth interstitialnephritisinapatientwithinflammatoryboweldisease
AT michelleparmley interstitialnephritisinapatientwithinflammatoryboweldisease
AT josetorrealba interstitialnephritisinapatientwithinflammatoryboweldisease
AT tamimhamdi interstitialnephritisinapatientwithinflammatoryboweldisease