Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy

Primary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis. We present a patient who presented with a hemorrhagic pericardial effusion. No malignant cells were evident on c...

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Main Authors: Lokesh Shahani, Michael Beckmann, Srikanth Vallurupalli
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/956089
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author Lokesh Shahani
Michael Beckmann
Srikanth Vallurupalli
author_facet Lokesh Shahani
Michael Beckmann
Srikanth Vallurupalli
author_sort Lokesh Shahani
collection DOAJ
description Primary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis. We present a patient who presented with a hemorrhagic pericardial effusion. No malignant cells were evident on cytological examination. He subsequently developed membranoproliferative glomerulonephritis requiring hemodialysis. Metastatic cardiac angiosarcoma was diagnosed 5 months later. To our knowledge, this is the first reported case of paraneoplastic membranoproliferative glomerulopathy associated with cardiac angiosarcoma.
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spelling doaj-art-becdc1bbc7d340af8d689deb9498ffdc2025-02-03T05:59:17ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/956089956089Cardiac Angiosarcoma-Associated Membranoproliferative GlomerulonephropathyLokesh Shahani0Michael Beckmann1Srikanth Vallurupalli2Department of Internal Medicine, Southern Illinois University School of Medicine, 701 N. First Street, Springfield, IL 62702, USAPathology Associates of Central Illinois LTD, Springfield, IL 62702, USADepartment of Internal Medicine, Southern Illinois University School of Medicine, 701 N. First Street, Springfield, IL 62702, USAPrimary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis. We present a patient who presented with a hemorrhagic pericardial effusion. No malignant cells were evident on cytological examination. He subsequently developed membranoproliferative glomerulonephritis requiring hemodialysis. Metastatic cardiac angiosarcoma was diagnosed 5 months later. To our knowledge, this is the first reported case of paraneoplastic membranoproliferative glomerulopathy associated with cardiac angiosarcoma.http://dx.doi.org/10.1155/2011/956089
spellingShingle Lokesh Shahani
Michael Beckmann
Srikanth Vallurupalli
Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
Case Reports in Medicine
title Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
title_full Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
title_fullStr Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
title_full_unstemmed Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
title_short Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy
title_sort cardiac angiosarcoma associated membranoproliferative glomerulonephropathy
url http://dx.doi.org/10.1155/2011/956089
work_keys_str_mv AT lokeshshahani cardiacangiosarcomaassociatedmembranoproliferativeglomerulonephropathy
AT michaelbeckmann cardiacangiosarcomaassociatedmembranoproliferativeglomerulonephropathy
AT srikanthvallurupalli cardiacangiosarcomaassociatedmembranoproliferativeglomerulonephropathy