Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1)
Abstract Introduction Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition...
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BMC
2025-01-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-025-05494-5 |
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| author | A. Pardo V. Vanti F. Lonardi A. Signoriello G. Lobbia G. Lombardo L. Trevisiol A. D’Agostino |
| author_facet | A. Pardo V. Vanti F. Lonardi A. Signoriello G. Lobbia G. Lombardo L. Trevisiol A. D’Agostino |
| author_sort | A. Pardo |
| collection | DOAJ |
| description | Abstract Introduction Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition of oral bacterial flora, while the second analyzes data on dental caries. Materials and Methods Four databases (PubMed, Cochrane, Scopus, Web of Science) were searched for studies that compared periodontal parameters, caries index, and microbiota composition between persons with cleft lip and/or palate and healthy controls. The Newcastle–Ottawa scale and the Joanna Briggs Institute checklist were applied to evaluate study quality. Results A total of 24 studies underwent systematic review, 18 of which entered meta-analysis. Twenty studies included a control group, while four included only persons with orofacial cleft. The first part (18 studies) compared periodontal parameters and oral microbiota. Conclusions Meta-analysis of periodontal parameters (plaque index, gingival index, bleeding index, probing pocket depth, clinical attachment level) revealed an association between orofacial cleft and greater risk for poor oral health and periodontal disease. Good oral health relies on correct home oral hygiene and regular visits to the dentist starting at an early age. |
| format | Article |
| id | doaj-art-bec52dfb77f4453c84d8d631d5fc93e0 |
| institution | Kabale University |
| issn | 1472-6831 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj-art-bec52dfb77f4453c84d8d631d5fc93e02025-02-02T12:45:22ZengBMCBMC Oral Health1472-68312025-01-0125111410.1186/s12903-025-05494-5Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1)A. Pardo0V. Vanti1F. Lonardi2A. Signoriello3G. Lobbia4G. Lombardo5L. Trevisiol6A. D’Agostino7Dentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaUnit of Maxillo-Facial Surgery, Santa Chiara Regional Hospital, APSSDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Paediatrics and Gynaecology (DIPSCOMI), University of VeronaAbstract Introduction Orofacial cleft impacts jawbone and dental development and function, often with consequences for oral health. The first in this two-part systematic review of the literature on oral health in persons with cleft lip and/or palate focuses on periodontal parameters and composition of oral bacterial flora, while the second analyzes data on dental caries. Materials and Methods Four databases (PubMed, Cochrane, Scopus, Web of Science) were searched for studies that compared periodontal parameters, caries index, and microbiota composition between persons with cleft lip and/or palate and healthy controls. The Newcastle–Ottawa scale and the Joanna Briggs Institute checklist were applied to evaluate study quality. Results A total of 24 studies underwent systematic review, 18 of which entered meta-analysis. Twenty studies included a control group, while four included only persons with orofacial cleft. The first part (18 studies) compared periodontal parameters and oral microbiota. Conclusions Meta-analysis of periodontal parameters (plaque index, gingival index, bleeding index, probing pocket depth, clinical attachment level) revealed an association between orofacial cleft and greater risk for poor oral health and periodontal disease. Good oral health relies on correct home oral hygiene and regular visits to the dentist starting at an early age.https://doi.org/10.1186/s12903-025-05494-5Cleft lip and/or palatePeriodontal parametersOral microbiota |
| spellingShingle | A. Pardo V. Vanti F. Lonardi A. Signoriello G. Lobbia G. Lombardo L. Trevisiol A. D’Agostino Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) BMC Oral Health Cleft lip and/or palate Periodontal parameters Oral microbiota |
| title | Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) |
| title_full | Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) |
| title_fullStr | Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) |
| title_full_unstemmed | Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) |
| title_short | Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1) |
| title_sort | oral health in patients with cleft lip and palate a systematic literature review and meta analysis of periodontal and dental disease and oral microbiota part 1 |
| topic | Cleft lip and/or palate Periodontal parameters Oral microbiota |
| url | https://doi.org/10.1186/s12903-025-05494-5 |
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