mSphere of Influence: How the single cell contributes to the collective
ABSTRACT Gina Lewin works in the field of microbial ecology, with a focus on the human microbiota. In this mSphere of Influence article, she reflects on how two papers describing bacterial single-cell RNA-seq—“Prokaryotic single-cell RNA sequencing by in situ combinatorial indexing” by S. B. Blattma...
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2025-01-01
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| Series: | mSphere |
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| Online Access: | https://journals.asm.org/doi/10.1128/msphere.00431-24 |
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| author | Gina R. Lewin |
| author_facet | Gina R. Lewin |
| author_sort | Gina R. Lewin |
| collection | DOAJ |
| description | ABSTRACT Gina Lewin works in the field of microbial ecology, with a focus on the human microbiota. In this mSphere of Influence article, she reflects on how two papers describing bacterial single-cell RNA-seq—“Prokaryotic single-cell RNA sequencing by in situ combinatorial indexing” by S. B. Blattman, W. Jiang, P. Oikonomou, and S. Tavazoie (Nat Microbiol 5:1192–1201, 2020, https://doi.org/10.1038/s41564-020-0729-6) and “Microbial single-cell RNA sequencing by split-pool barcoding” by A. Kuchina, L. M. Brettner, L. Paleologu, C. M. Roco, et al. (Science 371:eaba5257, 2021, https://doi.org/10.1126/science.aba5257)—impacted her work by developing a new approach to study how single cells of bacteria contribute to ecosystem-level processes. |
| format | Article |
| id | doaj-art-be8f291269f2485bad3f25e3785b895f |
| institution | Kabale University |
| issn | 2379-5042 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mSphere |
| spelling | doaj-art-be8f291269f2485bad3f25e3785b895f2025-01-28T14:00:56ZengAmerican Society for MicrobiologymSphere2379-50422025-01-0110110.1128/msphere.00431-24mSphere of Influence: How the single cell contributes to the collectiveGina R. Lewin0Department of Pathology, Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio, USAABSTRACT Gina Lewin works in the field of microbial ecology, with a focus on the human microbiota. In this mSphere of Influence article, she reflects on how two papers describing bacterial single-cell RNA-seq—“Prokaryotic single-cell RNA sequencing by in situ combinatorial indexing” by S. B. Blattman, W. Jiang, P. Oikonomou, and S. Tavazoie (Nat Microbiol 5:1192–1201, 2020, https://doi.org/10.1038/s41564-020-0729-6) and “Microbial single-cell RNA sequencing by split-pool barcoding” by A. Kuchina, L. M. Brettner, L. Paleologu, C. M. Roco, et al. (Science 371:eaba5257, 2021, https://doi.org/10.1126/science.aba5257)—impacted her work by developing a new approach to study how single cells of bacteria contribute to ecosystem-level processes.https://journals.asm.org/doi/10.1128/msphere.00431-24single-cell RNA-seqtranscriptional heterogeneitysubpopulations |
| spellingShingle | Gina R. Lewin mSphere of Influence: How the single cell contributes to the collective mSphere single-cell RNA-seq transcriptional heterogeneity subpopulations |
| title | mSphere of Influence: How the single cell contributes to the collective |
| title_full | mSphere of Influence: How the single cell contributes to the collective |
| title_fullStr | mSphere of Influence: How the single cell contributes to the collective |
| title_full_unstemmed | mSphere of Influence: How the single cell contributes to the collective |
| title_short | mSphere of Influence: How the single cell contributes to the collective |
| title_sort | msphere of influence how the single cell contributes to the collective |
| topic | single-cell RNA-seq transcriptional heterogeneity subpopulations |
| url | https://journals.asm.org/doi/10.1128/msphere.00431-24 |
| work_keys_str_mv | AT ginarlewin msphereofinfluencehowthesinglecellcontributestothecollective |