The Role of Epithelial–Mesenchymal Transition in Malignant Pleural Mesothelioma: From Pathogenesis to Diagnosis and Treatment

The Role of Epithelial–Mesenchymal Transition in Malignant Pleural Mesothelioma: From Pathogenesis to Diagnosis and Treatment

Malignant pleural mesothelioma (MPM) is an aggressive cancer of the pleural lining, primarily associated with asbestos exposure. Despite advancements in multimodal treatment, patient survival remains poor. Epithelial–mesenchymal transition (EMT) has emerged as a crucial process driving MPM pathogene...

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Bibliographic Details
Main Authors: Dimitrios E. Magouliotis, Fabrizio Minervini, Ugo Cioffi, Matilde De Simone, Davide Patrini, Marco Scarci
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
epithelial–mesenchymal transition
EMT
malignant pleural mesothelioma
MPM
immunotherapy
biomarkers
Online Access:https://www.mdpi.com/2073-4409/14/8/585
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