Trade-off between resistance and persistence in high cell density cultures

Trade-off between resistance and persistence in high cell density cultures

ABSTRACT Bacterial growth to high cell densities is commonly observed in infections, microbiomes, and biomanufacturing, yet there is limited understanding of how transcriptional regulation changes to balance between growth and survival under associated stresses. Here, we utilized well-controlled cul...

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Bibliographic Details
Main Authors: F. Beulig, J. Bafna-Rührer, P. E. Jensen, S. H. Kim, A. Patel, V. Kandasamy, C. Steffen, K. Decker, D. Zielinski, L. Yang, E. Özdemir, S. Sudarsan, B. Palsson
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSystems
Subjects:
Escherichia coli
high cell density physiology
persistence
resistance
stimulons
Online Access:https://journals.asm.org/doi/10.1128/msystems.00323-25
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