Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS

Gestational diabetes mellitus is a worldwide health issue in pregnancy, posing a threat to both mother and child. One of the major risk factors for the development of gestational diabetes mellitus is polycystic ovary syndrome, primarily due to the biochemical hyperandrogenism and metabolic issues, c...

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Main Authors: Paola Quaresima, Samuel H. Myers, Basilio Pintaudi, Rosario D’Anna, Michele Morelli, Vittorio Unfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1501110/full
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author Paola Quaresima
Samuel H. Myers
Basilio Pintaudi
Basilio Pintaudi
Rosario D’Anna
Rosario D’Anna
Michele Morelli
Vittorio Unfer
Vittorio Unfer
author_facet Paola Quaresima
Samuel H. Myers
Basilio Pintaudi
Basilio Pintaudi
Rosario D’Anna
Rosario D’Anna
Michele Morelli
Vittorio Unfer
Vittorio Unfer
author_sort Paola Quaresima
collection DOAJ
description Gestational diabetes mellitus is a worldwide health issue in pregnancy, posing a threat to both mother and child. One of the major risk factors for the development of gestational diabetes mellitus is polycystic ovary syndrome, primarily due to the biochemical hyperandrogenism and metabolic issues, commonly observed in these patients. In recent years, the Expert Group on Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS) has sought to better understand the pathogenesis behind polycystic ovary syndrome, in order to accurately diagnose and treat patients according to their individual needs. Through the scope of polycystic ovary syndrome, this position paper examines the characteristics of both conditions, and underlying biological mechanisms, before moving on to common treatment strategies to avoid or treat gestational diabetes mellitus in women with polycystic ovary syndrome.
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series Frontiers in Endocrinology
spelling doaj-art-be60fd8674e44d2eacb73fd63d5cf4372025-01-31T05:10:17ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-01-011610.3389/fendo.2025.15011101501110Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOSPaola Quaresima0Samuel H. Myers1Basilio Pintaudi2Basilio Pintaudi3Rosario D’Anna4Rosario D’Anna5Michele Morelli6Vittorio Unfer7Vittorio Unfer8Department of Obstetrics and Gynecology, Azienda Sanitaria Provinciale di Cosenza, Cosenza, ItalyR&D Department, Lo.Li Pharma s.r.l, Rome, ItalyThe Experts Group on Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS), Rome, ItalyAzienda Socio Sanitaria Territoriale (ASST) Grande Ospedale Metropolitano Niguarda, Milan, ItalyThe Experts Group on Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS), Rome, ItalyDepartment of Human Pathology, University of Messina, Messina, ItalyDepartment of Obstetrics and Gynecology, Annunziata Hospital, Cosenza, ItalyThe Experts Group on Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS), Rome, ItalyUniCamillus-Saint Camillus International University of Health Sciences, Rome, ItalyGestational diabetes mellitus is a worldwide health issue in pregnancy, posing a threat to both mother and child. One of the major risk factors for the development of gestational diabetes mellitus is polycystic ovary syndrome, primarily due to the biochemical hyperandrogenism and metabolic issues, commonly observed in these patients. In recent years, the Expert Group on Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS) has sought to better understand the pathogenesis behind polycystic ovary syndrome, in order to accurately diagnose and treat patients according to their individual needs. Through the scope of polycystic ovary syndrome, this position paper examines the characteristics of both conditions, and underlying biological mechanisms, before moving on to common treatment strategies to avoid or treat gestational diabetes mellitus in women with polycystic ovary syndrome.https://www.frontiersin.org/articles/10.3389/fendo.2025.1501110/fullgestational diabetes mellituspolycystic ovary syndromeinsulinmetforminmyo-inositol
spellingShingle Paola Quaresima
Samuel H. Myers
Basilio Pintaudi
Basilio Pintaudi
Rosario D’Anna
Rosario D’Anna
Michele Morelli
Vittorio Unfer
Vittorio Unfer
Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
Frontiers in Endocrinology
gestational diabetes mellitus
polycystic ovary syndrome
insulin
metformin
myo-inositol
title Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
title_full Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
title_fullStr Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
title_full_unstemmed Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
title_short Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS
title_sort gestational diabetes mellitus and polycystic ovary syndrome a position statement from egoi pcos
topic gestational diabetes mellitus
polycystic ovary syndrome
insulin
metformin
myo-inositol
url https://www.frontiersin.org/articles/10.3389/fendo.2025.1501110/full
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