MAVS phosphorylation acts as a cellular stress sensor that modulates antiviral immunity

MAVS phosphorylation acts as a cellular stress sensor that modulates antiviral immunity

Summary: Upon viral infection, cytosolic RIG-I-like receptors recognize viral RNA and activate innate immune responses through the mitochondrial antiviral-signaling protein (MAVS), leading to type I interferon (IFN) production and apoptosis. Cellular stress influences immune activation, but its impa...

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Bibliographic Details
Main Authors: Dongyi Zhao, Nao Morimoto, Riho Saito, Juri Yamada, Shuntaro Abe, Hidetaka Kosako, Yukiko Gotoh, Tomohiko Okazaki
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:iScience
Subjects:
Biochemistry
Immune response
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225015172
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