Comprehensive analysis of peripheral blood free amino acids in MASLD: the impact of glycine-serine-threonine metabolism

Comprehensive analysis of peripheral blood free amino acids in MASLD: the impact of glycine-serine-threonine metabolism

Abstract Little is known about how blood free amino acids (FAAs) change in metabolic dysfunction-associated steatotic liver disease (MASLD). This study aims to identify the imbalance of FAAs in MASLD and explore its correction as a potential therapeutic target. We analyzed plasma FAAs data from 23,0...

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Main Authors: Masaaki Mino, Eiji Kakazu, Akitoshi Sano, Mio Tsuruoka, Hiroko Matsubara, Keisuke Kakisaka, Takayuki Kogure, Katsunori Sekine, Yoshihiko Aoki, Masatoshi Imamura, Michitaka Matsuda, Taiji Yamazoe, Taizo Mori, Sachiyo Yoshio, Jun Inoue, Atsushi Masamune, Tatsuya Kanto
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Amino Acids
Subjects:
SLD
MetALD
MASH
NASH
Cardiometabolic criteria
Online Access:https://doi.org/10.1007/s00726-024-03433-2
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