Disruption of BCAA degradation is a critical characteristic of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis
In this study, we integrated transcriptomic and metabolomic analyses to achieve a comprehensive understanding of the underlying mechanisms of diabetic cardiomyopathy (DCM) in a diabetic rat model. Functional and molecular characterizations revealed significant cardiac injury, dysfunction, and ventri...
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Main Authors: | Wu Yanxia, Jiang Wanxiang, Wang Junlong, Xie Guoqing, Sun Yan, Yang Jinliang |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2024-12-01
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Series: | Open Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1515/biol-2022-0974 |
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