Disruption of BCAA degradation is a critical characteristic of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis

In this study, we integrated transcriptomic and metabolomic analyses to achieve a comprehensive understanding of the underlying mechanisms of diabetic cardiomyopathy (DCM) in a diabetic rat model. Functional and molecular characterizations revealed significant cardiac injury, dysfunction, and ventri...

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Bibliographic Details
Main Authors: Wu Yanxia, Jiang Wanxiang, Wang Junlong, Xie Guoqing, Sun Yan, Yang Jinliang
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Open Life Sciences
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Online Access:https://doi.org/10.1515/biol-2022-0974
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