Steroid-Resistant Nephrotic Syndrome Is Associated With a Unique Genetic Profile in a Highly Admixed Pediatric Population

Steroid-Resistant Nephrotic Syndrome Is Associated With a Unique Genetic Profile in a Highly Admixed Pediatric Population

Introduction: The profile of genetic and nongenetic factors associated with progression to kidney failure (KF) in steroid-resistant nephrotic syndrome (SRNS) is largely unknown in admixed populations. Methods: A total of 101 pediatric patients with primary SRNS were genetically assessed targeting Me...

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Main Authors: Andreia Watanabe, Precil Diego Miranda de Menezes Neves, Kelly Nunes, Antonio Marcondes Lerario, Elieser Hitoshi Watanabe, Frederico Moraes Ferreira, Denise Maria Avancini Costa Malheiros, Amanda de Moraes Narcizo, Mara Sanches Guaragna, Stanley de Almeida Araujo, Thais Medeiros Cruz, Jussara Soares Fontes, Vera Maria Santoro Belangero, Maria Helena Vaisbich, Friedhelm Hildebrandt, Matthew Gordon Sampson, Luiz Fernando Onuchic
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Kidney International Reports
Subjects:
APOL1
children
focal segmental glomerulosclerosis
genetic ancestry
monogenic chronic kidney disease
steroid-resistant nephrotic syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924019235
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