EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1

Background: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.

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Main Authors: Helene Geddert, Axel zur Hausen, Helmut E. Gabbert, Mario Sarbia
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-CLO-2010-0540
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author Helene Geddert
Axel zur Hausen
Helmut E. Gabbert
Mario Sarbia
author_facet Helene Geddert
Axel zur Hausen
Helmut E. Gabbert
Mario Sarbia
author_sort Helene Geddert
collection DOAJ
description Background: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.
format Article
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institution Kabale University
issn 2210-7177
2210-7185
language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-be136500d9b5424685205f16819f151d2025-02-03T05:49:45ZengWileyAnalytical Cellular Pathology2210-71772210-71852010-01-01333-414314910.3233/ACP-CLO-2010-0540EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1Helene Geddert0Axel zur Hausen1Helmut E. Gabbert2Mario Sarbia3Institute of Pathology, University Hospital of Düsseldorf, Düsseldorf, GermanyInstitute of Pathology, University Hospital of Freiburg, Freiburg, GermanyInstitute of Pathology, University Hospital of Düsseldorf, Düsseldorf, GermanyInstitute of Pathology, Technical University of Munich, Munich, GermanyBackground: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.http://dx.doi.org/10.3233/ACP-CLO-2010-0540
spellingShingle Helene Geddert
Axel zur Hausen
Helmut E. Gabbert
Mario Sarbia
EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
Analytical Cellular Pathology
title EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
title_full EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
title_fullStr EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
title_full_unstemmed EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
title_short EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
title_sort ebv infection in cardiac and non cardiac gastric adenocarcinomas is associated with promoter methylation of p16 p14 and apc but not hmlh1
url http://dx.doi.org/10.3233/ACP-CLO-2010-0540
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