EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1
Background: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.
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Format: | Article |
Language: | English |
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Wiley
2010-01-01
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Series: | Analytical Cellular Pathology |
Online Access: | http://dx.doi.org/10.3233/ACP-CLO-2010-0540 |
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author | Helene Geddert Axel zur Hausen Helmut E. Gabbert Mario Sarbia |
author_facet | Helene Geddert Axel zur Hausen Helmut E. Gabbert Mario Sarbia |
author_sort | Helene Geddert |
collection | DOAJ |
description | Background: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV. |
format | Article |
id | doaj-art-be136500d9b5424685205f16819f151d |
institution | Kabale University |
issn | 2210-7177 2210-7185 |
language | English |
publishDate | 2010-01-01 |
publisher | Wiley |
record_format | Article |
series | Analytical Cellular Pathology |
spelling | doaj-art-be136500d9b5424685205f16819f151d2025-02-03T05:49:45ZengWileyAnalytical Cellular Pathology2210-71772210-71852010-01-01333-414314910.3233/ACP-CLO-2010-0540EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1Helene Geddert0Axel zur Hausen1Helmut E. Gabbert2Mario Sarbia3Institute of Pathology, University Hospital of Düsseldorf, Düsseldorf, GermanyInstitute of Pathology, University Hospital of Freiburg, Freiburg, GermanyInstitute of Pathology, University Hospital of Düsseldorf, Düsseldorf, GermanyInstitute of Pathology, Technical University of Munich, Munich, GermanyBackground: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.http://dx.doi.org/10.3233/ACP-CLO-2010-0540 |
spellingShingle | Helene Geddert Axel zur Hausen Helmut E. Gabbert Mario Sarbia EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 Analytical Cellular Pathology |
title | EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 |
title_full | EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 |
title_fullStr | EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 |
title_full_unstemmed | EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 |
title_short | EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1 |
title_sort | ebv infection in cardiac and non cardiac gastric adenocarcinomas is associated with promoter methylation of p16 p14 and apc but not hmlh1 |
url | http://dx.doi.org/10.3233/ACP-CLO-2010-0540 |
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