Low platelet count during pregnancy

Thrombocytopenia, a platelet count below 150,000/mm3, is the second most common hematological disorder during pregnancy, following anemia. It affects approximately 7–10% of pregnant women and may result from physiological changes or underlying pathological conditions, some of which can have serious...

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Main Authors: Trupti Agrawal, Aditi Kaundinya, Anuya Pawde
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:MGM Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.4103/mgmj.mgmj_91_25
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author Trupti Agrawal
Aditi Kaundinya
Anuya Pawde
author_facet Trupti Agrawal
Aditi Kaundinya
Anuya Pawde
author_sort Trupti Agrawal
collection DOAJ
description Thrombocytopenia, a platelet count below 150,000/mm3, is the second most common hematological disorder during pregnancy, following anemia. It affects approximately 7–10% of pregnant women and may result from physiological changes or underlying pathological conditions, some of which can have serious maternal and fetal consequences. This study was conducted at a tertiary care center in Navi Mumbai to assess the causes, management, and maternal outcomes associated with thrombocytopenia in pregnancy. Over one year, 12 cases were examined. Among these, 50% were diagnosed with gestational thrombocytopenia (GT), 16% with immune thrombocytopenic purpura (ITP), another 16% with dengue-related thrombocytopenia, 10% with hypertensive disorders of pregnancy, and 8% with hereditary thrombocytopenia. Treatment strategies varied based on the underlying cause, including platelet transfusions, corticosteroids, and intravenous immunoglobulin. While GT was typically mild with favorable outcomes, more severe conditions such as ITP and hypertensive disorders required coordinated, multidisciplinary care. Prompt diagnosis, targeted treatment, and planned institutional deliveries were crucial in minimizing complications and achieving positive maternal and fetal outcomes.
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spelling doaj-art-bdfd9608f03e47d7b5fbc7b093df274b2025-08-20T03:34:01ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622025-04-0112238338810.4103/mgmj.mgmj_91_25Low platelet count during pregnancyTrupti AgrawalAditi KaundinyaAnuya PawdeThrombocytopenia, a platelet count below 150,000/mm3, is the second most common hematological disorder during pregnancy, following anemia. It affects approximately 7–10% of pregnant women and may result from physiological changes or underlying pathological conditions, some of which can have serious maternal and fetal consequences. This study was conducted at a tertiary care center in Navi Mumbai to assess the causes, management, and maternal outcomes associated with thrombocytopenia in pregnancy. Over one year, 12 cases were examined. Among these, 50% were diagnosed with gestational thrombocytopenia (GT), 16% with immune thrombocytopenic purpura (ITP), another 16% with dengue-related thrombocytopenia, 10% with hypertensive disorders of pregnancy, and 8% with hereditary thrombocytopenia. Treatment strategies varied based on the underlying cause, including platelet transfusions, corticosteroids, and intravenous immunoglobulin. While GT was typically mild with favorable outcomes, more severe conditions such as ITP and hypertensive disorders required coordinated, multidisciplinary care. Prompt diagnosis, targeted treatment, and planned institutional deliveries were crucial in minimizing complications and achieving positive maternal and fetal outcomes.https://doi.org/10.4103/mgmj.mgmj_91_25gestationalpregnancythrombocytopenia
spellingShingle Trupti Agrawal
Aditi Kaundinya
Anuya Pawde
Low platelet count during pregnancy
MGM Journal of Medical Sciences
gestational
pregnancy
thrombocytopenia
title Low platelet count during pregnancy
title_full Low platelet count during pregnancy
title_fullStr Low platelet count during pregnancy
title_full_unstemmed Low platelet count during pregnancy
title_short Low platelet count during pregnancy
title_sort low platelet count during pregnancy
topic gestational
pregnancy
thrombocytopenia
url https://doi.org/10.4103/mgmj.mgmj_91_25
work_keys_str_mv AT truptiagrawal lowplateletcountduringpregnancy
AT aditikaundinya lowplateletcountduringpregnancy
AT anuyapawde lowplateletcountduringpregnancy