Exopeptidase combination enhances the degradation of isotopically labelled gluten immunogenic peptides in humans

IntroductionCeliac disease is a common autoimmune-like enteropathy caused by an aberrant response to incompletely digested dietary gluten. Gluten immunogenic peptides including the immunodominant 33-mer are thought to be resistant to proteolytic digestion by human gastrointestinal peptidases. We dev...

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Bibliographic Details
Main Authors: Sulayman Mourabit, Sarah Römer, Erin R. Bonner, Fabian Winter, Julian Tschollar, Mladen V. Tzvetkov, Werner Weitschies, Stefan Engeli, Werner Tschollar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1425982/full
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