Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature
A 40-year-old woman was admitted due to an urticarial rash that was attributed to recent onset of methimazole treatment for a diagnosis of Grave’s disease. The patient had no prior significant medical history and used no medications, including over-the-counter or herbal medications. Her sister had G...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2015/649303 |
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| author | Tawfik Khoury Ronen Schneider |
| author_facet | Tawfik Khoury Ronen Schneider |
| author_sort | Tawfik Khoury |
| collection | DOAJ |
| description | A 40-year-old woman was admitted due to an urticarial rash that was attributed to recent onset of methimazole treatment for a diagnosis of Grave’s disease. The patient had no prior significant medical history and used no medications, including over-the-counter or herbal medications. Her sister had Grave’s disease. On admission, the patient received corticosteroids with improvement in her rash. On the second day of the hospitalization, the patient complained of abdominal discomfort. Abdominal ultrasound revealed a large amount of new onset ascites. Peritoneal tap yielded a milky fluid with high triglyceride level (12.2 mmol/L or 1080 mg/dL), consistent with chylous ascites. After discontinuation of the methimazole, the ascites disappeared. The patient later underwent therapeutic thyroidectomy, after which all features of thyrotoxicosis had improved. |
| format | Article |
| id | doaj-art-bdd2e9cc58844e9d9c1491be8bc63a9f |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-bdd2e9cc58844e9d9c1491be8bc63a9f2025-02-03T05:57:11ZengWileyCase Reports in Endocrinology2090-65012090-651X2015-01-01201510.1155/2015/649303649303Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the LiteratureTawfik Khoury0Ronen Schneider1Department of Medicine, Hadassah-Hebrew University Medical Center, P.O. Box 12000, IL-91120 Jerusalem, IsraelDepartment of Nephrology, Hadassah-Hebrew University Medical Center, P.O. Box 12000, IL-91120 Jerusalem, IsraelA 40-year-old woman was admitted due to an urticarial rash that was attributed to recent onset of methimazole treatment for a diagnosis of Grave’s disease. The patient had no prior significant medical history and used no medications, including over-the-counter or herbal medications. Her sister had Grave’s disease. On admission, the patient received corticosteroids with improvement in her rash. On the second day of the hospitalization, the patient complained of abdominal discomfort. Abdominal ultrasound revealed a large amount of new onset ascites. Peritoneal tap yielded a milky fluid with high triglyceride level (12.2 mmol/L or 1080 mg/dL), consistent with chylous ascites. After discontinuation of the methimazole, the ascites disappeared. The patient later underwent therapeutic thyroidectomy, after which all features of thyrotoxicosis had improved.http://dx.doi.org/10.1155/2015/649303 |
| spellingShingle | Tawfik Khoury Ronen Schneider Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature Case Reports in Endocrinology |
| title | Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature |
| title_full | Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature |
| title_fullStr | Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature |
| title_full_unstemmed | Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature |
| title_short | Chylous Ascites: A Rare Adverse Effect of Methimazole Treatment for Grave’s Disease—A Case Report and Review of the Literature |
| title_sort | chylous ascites a rare adverse effect of methimazole treatment for grave s disease a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2015/649303 |
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