Design, Synthesis, and Biological Evaluation of New Analogs of Aurein 1.2 Containing Non-Proteinogenic Amino Acids

Design, Synthesis, and Biological Evaluation of New Analogs of Aurein 1.2 Containing Non-Proteinogenic Amino Acids

Extensive use of classical antibiotics has led to the growing emergence of many resistant strains of pathogenic bacteria. To combat this challenge, researchers have turned to the antimicrobial peptides (AMPs). Aurein 1.2 (GLFDIIKKIAESF-NH2) was demonstrated to have broad spectrum bi-functionality ag...

Full description

Saved in:
Bibliographic Details
Main Authors: Nora Angelova, Ivan Iliev, Veronica Nemska, Tatyana Dzimbova, Nelly Georgieva, Dancho Danalev, Emilia Naydenova
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
antimicrobial peptides (AMPs)
aurein 1.2
antimicrobial activity
antiproliferative activity
nonproteinogenic amino acids
secondary structure prediction
Online Access:https://www.mdpi.com/1420-3049/30/9/2050
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/30/9/2050

Similar Items