Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration- Tobacco working group rationale, design, and methodology
While the impact of combustible cigarette smoking on cardiovascular disease (CVD) is well-established, the longitudinal association of non-traditional tobacco products with subclinical and clinical CVD has not been fully explored due to: 1) limited data availability; and 2) the lack of well-phenotyp...
Saved in:
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2023-07-01
|
| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | https://www.tobaccoinduceddiseases.org/Investigating-the-association-of-traditional-and-non-traditional-tobacco-product,166517,0,2.html |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587244292014080 |
|---|---|
| author | Erfan Tasdighi Kunal K. Jha Zeina A. Dardari Ngozi Osuji Tanuja Rajan Ellen Boakye Michael E. Hall Carlos J. Rodriguez Andrew C. Stokes Omar El Shahawy Emelia J. Benjamin Aruni Bhatnagar Andrew P. DeFilippis Michael J. Blaha |
| author_facet | Erfan Tasdighi Kunal K. Jha Zeina A. Dardari Ngozi Osuji Tanuja Rajan Ellen Boakye Michael E. Hall Carlos J. Rodriguez Andrew C. Stokes Omar El Shahawy Emelia J. Benjamin Aruni Bhatnagar Andrew P. DeFilippis Michael J. Blaha |
| author_sort | Erfan Tasdighi |
| collection | DOAJ |
| description | While the impact of combustible cigarette smoking on cardiovascular disease
(CVD) is well-established, the longitudinal association of non-traditional tobacco
products with subclinical and clinical CVD has not been fully explored due to: 1)
limited data availability; and 2) the lack of well-phenotyped prospective cohorts.
Therefore, there is the need for sufficiently powered well-phenotyped datasets
to fully elucidate the CVD risks associated with non-cigarette tobacco products.
The Cross-Cohort Collaboration (CCC)-Tobacco is a harmonized dataset of 23
prospective cohort studies predominantly in the US. A priori defined variables
collected from each cohort included baseline characteristics, details of traditional
and non-traditional tobacco product use, inflammatory markers, and outcomes
including subclinical and clinical CVD. The definitions of the variables in each
cohort were systematically evaluated by a team of two physician-scientists
and a biostatistician. Herein, we describe the method of data acquisition and
harmonization and the baseline sociodemographic and risk profile of participants
in the combined CCC-Tobacco dataset. The total number of participants in
the pooled cohort is 322782 (mean age: 59.7 ± 11.8 years) of which 76% are
women. White individuals make up the majority (73.1%), although there is good
representation of other race and ethnicity groups including African American
(15.6%) and Hispanic/Latino individuals (6.4%). The prevalence of participants
who never smoked, formerly smoked, and currently smoke combustible cigarettes
is 50%, 36%, and 14%, respectively. The prevalence of current and former cigar,
pipe, and smokeless tobacco is 7.3%, 6.4%, and 8.6%, respectively. E-cigarette
use was measured only in follow-up visits of select studies, totaling 1704 former
and current users. CCC-Tobacco is a large, pooled cohort dataset that is uniquely
designed with increased power to expand knowledge regarding the association
of traditional and non-traditional tobacco use with subclinical and clinical CVD,
with extension to understudied groups including women and individuals from
underrepresented racial-ethnic groups. |
| format | Article |
| id | doaj-art-bdc3cc5e672b4e25b0da6fdf26e74301 |
| institution | Kabale University |
| issn | 1617-9625 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Tobacco Induced Diseases |
| spelling | doaj-art-bdc3cc5e672b4e25b0da6fdf26e743012025-01-24T15:26:37ZengEuropean PublishingTobacco Induced Diseases1617-96252023-07-0121July11710.18332/tid/166517166517Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration- Tobacco working group rationale, design, and methodologyErfan Tasdighi0Kunal K. Jha1Zeina A. Dardari2Ngozi Osuji3Tanuja Rajan4Ellen Boakye5Michael E. Hall6Carlos J. Rodriguez7Andrew C. Stokes8Omar El Shahawy9Emelia J. Benjamin10Aruni Bhatnagar11Andrew P. DeFilippis12Michael J. Blaha13https://orcid.org/0000-0001-5138-9683Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesAmerican Heart Association Tobacco Regulation and Addiction Center, Dallas, United StatesJohns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, United StatesWhile the impact of combustible cigarette smoking on cardiovascular disease (CVD) is well-established, the longitudinal association of non-traditional tobacco products with subclinical and clinical CVD has not been fully explored due to: 1) limited data availability; and 2) the lack of well-phenotyped prospective cohorts. Therefore, there is the need for sufficiently powered well-phenotyped datasets to fully elucidate the CVD risks associated with non-cigarette tobacco products. The Cross-Cohort Collaboration (CCC)-Tobacco is a harmonized dataset of 23 prospective cohort studies predominantly in the US. A priori defined variables collected from each cohort included baseline characteristics, details of traditional and non-traditional tobacco product use, inflammatory markers, and outcomes including subclinical and clinical CVD. The definitions of the variables in each cohort were systematically evaluated by a team of two physician-scientists and a biostatistician. Herein, we describe the method of data acquisition and harmonization and the baseline sociodemographic and risk profile of participants in the combined CCC-Tobacco dataset. The total number of participants in the pooled cohort is 322782 (mean age: 59.7 ± 11.8 years) of which 76% are women. White individuals make up the majority (73.1%), although there is good representation of other race and ethnicity groups including African American (15.6%) and Hispanic/Latino individuals (6.4%). The prevalence of participants who never smoked, formerly smoked, and currently smoke combustible cigarettes is 50%, 36%, and 14%, respectively. The prevalence of current and former cigar, pipe, and smokeless tobacco is 7.3%, 6.4%, and 8.6%, respectively. E-cigarette use was measured only in follow-up visits of select studies, totaling 1704 former and current users. CCC-Tobacco is a large, pooled cohort dataset that is uniquely designed with increased power to expand knowledge regarding the association of traditional and non-traditional tobacco use with subclinical and clinical CVD, with extension to understudied groups including women and individuals from underrepresented racial-ethnic groups.https://www.tobaccoinduceddiseases.org/Investigating-the-association-of-traditional-and-non-traditional-tobacco-product,166517,0,2.htmlcross-cohort collaborationtobacco smokingnon-cigarette tobaccoe-cigarettecardiovascular disease |
| spellingShingle | Erfan Tasdighi Kunal K. Jha Zeina A. Dardari Ngozi Osuji Tanuja Rajan Ellen Boakye Michael E. Hall Carlos J. Rodriguez Andrew C. Stokes Omar El Shahawy Emelia J. Benjamin Aruni Bhatnagar Andrew P. DeFilippis Michael J. Blaha Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration- Tobacco working group rationale, design, and methodology Tobacco Induced Diseases cross-cohort collaboration tobacco smoking non-cigarette tobacco e-cigarette cardiovascular disease |
| title | Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-
Tobacco working group rationale, design, and methodology |
| title_full | Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-
Tobacco working group rationale, design, and methodology |
| title_fullStr | Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-
Tobacco working group rationale, design, and methodology |
| title_full_unstemmed | Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-
Tobacco working group rationale, design, and methodology |
| title_short | Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-
Tobacco working group rationale, design, and methodology |
| title_sort | investigating the association of traditional and non traditional tobacco product use with subclinical and clinical cardiovascular disease the cross cohort collaboration tobacco working group rationale design and methodology |
| topic | cross-cohort collaboration tobacco smoking non-cigarette tobacco e-cigarette cardiovascular disease |
| url | https://www.tobaccoinduceddiseases.org/Investigating-the-association-of-traditional-and-non-traditional-tobacco-product,166517,0,2.html |
| work_keys_str_mv | AT erfantasdighi investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT kunalkjha investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT zeinaadardari investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT ngoziosuji investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT tanujarajan investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT ellenboakye investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT michaelehall investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT carlosjrodriguez investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT andrewcstokes investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT omarelshahawy investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT emeliajbenjamin investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT arunibhatnagar investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT andrewpdefilippis investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology AT michaeljblaha investigatingtheassociationoftraditionalandnontraditionaltobaccoproductusewithsubclinicalandclinicalcardiovasculardiseasethecrosscohortcollaborationtobaccoworkinggrouprationaledesignandmethodology |